Faculty Profiles
Major Equipments
Major Research Areas
Sponsored Projects
P Gopinath
Dr. P.Gopinath Associate Professor pgopifnt[at] 01332285650 Website
Areas of Interest
  • Cancer nanotechnology, Drug delivery, Biomaterials, Bioimaging , Tissue engineering, Environmental nanotechnology
Professional Background
29.04.2016-till dateAssociate ProfessorIIT Roorkee, Roorkee, Uttarakhand.
06.06.201128.04.2016Assistant ProfessorIIT Roorkee, Roorkee, Uttarakhand.
23.09.201013.05.2011Assistant ProfessorAmrita University Coimbatore, Tamil Nadu.
20.10.200802.06.2010Post-Doctoral Research AssociateUniversity of Rochester Medical Center, Rochester, New York, USA.
04.01.200814.09.2008Senior Research FellowIIT Guwahati Department of Biotechnology, Guwahati, Assam
Educational Details
Ph.D.BiotechnologyIndian Institute of Technology (IIT) Guwahati2008
M.Sc.Biotechnology Srimad Andavan Arts and Science College, Bharathidasan University, Trichy2003
B.Sc.Microbiology Srimad Andavan Arts and Science College, Bharathidasan University, Trichy2001
Administrative Background
01.07.201230.06.2014Member (Nanotechnology)Institute Academic Programme Committee (IAPC)
April 2012June 2014Member (Nanotechnology)Board of Research
July 2011April 2015Faculty-in-charge (Nanotechnology) Training & Placement
  • Indian Nanoscience society , Life member
  • Society for Biomaterials and Artificial Organs , Life member
  • Society for Tissue Engineering and Regenerative Medicine , Life member
  • Indian Science Congress Association , Life member
  • Indian society of chemists and Biologists , Life member
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Year
Development of albumin based nanoparticles for biomedical applicationsBharat BhushanA2011
Silver nanoparticle and graphene oxide based nanocomposites for biomedical applicationsPoornima DubeyA2010
Development of carbon dots based multifunctional nanomaterials for potential applicationsAbhay SachdevA2013
Poly(amidoamine) dendrimer based nanomaterials for delivery of anticancer agentsIshita MataiA2013
Development of biofunctional polymeric nanofibers and their therapeutic implicationsS. Uday KumarA2012
Special Lectures Delivered
Nano-remediation: Applications of nanotechnology for water purificationNIT Tiruchirappalli13.06.2016
Nanotoxicology : Cytotoxic and Genotoxic Potential of NanomaterialsNIT Tiruchirappalli13.06.2016
Cancer Nanotechnology: Applications of Nanomaterials for Cancer Diagnosis and Therapy SASTRA University13.02.2015
Nanomedicinal Properties of Silver NanoparticlesAnnamalai University09.01.2012
Promising Nanoscale Approaches for Cancer Diagnosis and Therapy IFTM University05.11.2016
Books Authored


Book chapters

  • S.Raj Kumar and P. Gopinath*, ‘Nano-Bioremediation: Applications of Nanotechnology for Bioremediation’ in book titled “Remediation of Heavy Metals in the Environment” CRC Press (2016) (in press).
  • A. Sachdev, S. Uday Kumar, I. Matai, G. Bhargavi, P. Dubey, B. Bhushan and P.Gopinath*. ‘Polymers as nanocarrier for cancer theranostic applications’ in book titled “Recent Developments in Carbohydrates Polymer Research” Research Signpost Publishers (2014) chapter 4, page no. 45-55, ISBN: 978-81-308-0534-4
  • I. Matai, A. Sachdev, S. Uday Kumar, P. Dubey, B. Bhushan and P.Gopinath* ‘Dendrimer: A promising nanocarrier for cancer therapy’ in book titled “Nanotechnology: Recent Trends, Emerging Issues and Future Directions” Nova publishers (2014) chapter 7, page no. 127-155, ISBN 978-1-63117-561-9.
Refereed Journal Papers
  1. B. Tirkey, B. Bhushan, S.Uday Kumar and P.Gopinath*. Prodrug encapsulated albumin nanoparticles as an alternative approach to manifest anti-proliferative effects of suicide gene therapy. Materials Science & Engineering C, 2017, 73, 507–515

  2. Sauraj, S.Uday Kumar, P.Gopinath, Y.S. Negi. Synthesis and bio-evaluation of xylan-5-fluorouracil-1-acetic acid conjugates as prodrugs for colon cancer treatment. Carbohydrate Polymers, 2017, 157,1442–1450 

  3. N. Singh, A. Sachdev and P. Gopinath*, Polysaccharide functionalized single walled carbon nanotubes as nanocarriers for delivery of curcumin in lung cancer cells. Journal of Nanoscience and Nanotechnology, 2017, (in press) 

  4. N. Pal, P.Dubey, P.Gopinath, K. Pal. Combined effect of cellulose nanocrystal and reduced graphene oxide into poly-lactic acid matrix nanocomposite as a scaffold and its anti-bacterial activity. International Journal of Biological Macromolecules, 2017, 95, 94–105

  5. S.Raj Kumar and P. Gopinath*, In situ synthesis of chitosan coated silver-zinc oxide nanocomposites and its enhanced antibacterial properties. Journal of Nanoscience and Nanotechnology, 2017, 17, 1–9 

  6. D. Malwal and P.Gopinath*. Efficient adsorption and antibacterial properties of electrospun CuO-ZnO composite nanofibers for water remediation. Journal of Hazardous Materials, 2017, 321, 611–621 

  7. D. Malwal and P. Gopinath*, Rapid and efficient removal of arsenic from water using electrospun CuO-ZnO composite nanofibers.RSC Advances, 2016, 6, 115021-115028

  8. S.Raj Kumar and P. Gopinath*, Dual applications of silver nanoparticles incorporated functionalized MWCNTs grafted surface modified PAN nanofibrous membrane for water purification. RSC Advances, 2016, 6, 109241 - 109252

  9. P.Dubey and P.Gopinath*. Functionalized Graphene Oxide based Nanocarrier for Tumor-Targeted Combination Therapy to Elicit Enhanced Cytotoxicity against Breast Cancer cells in vitro. ChemistrySelect, 2016, 1, 4845 – 4855.

  10. P.Dubey and P.Gopinath*. PEGylated Graphene Oxide based Nanocomposite grafted Chitosan/Polyvinyl alcohol Nanofiber as an Advanced Antibacterial Wound Dressing. RSC Advances, 2016, 6, 69103-69116

  11. B.Bhushan, S.Nandhagopal, R.Rajesh Kannan and P.Gopinath*. Therapeutic Nanozyme: Antioxidative and cytoprotective effects of nanoceria against hydrogen peroxide induced oxidative stress in fibroblast cells and in zebrafish. ChemistrySelect, 2016, 1, 2849 – 2856

  12. B. Bhushan, S.Uday Kumar and P.Gopinath*. Multifunctional carbon dots as efficient fluorescent nanotags for tracking cells through successive generations. Journal of Materials Chemistry B, 2016, 4, 4862-4871  

  13. B.Bhushan,S.Nandhagopal, R.Rajesh Kannan and P.Gopinath*. Biomimetic nanomaterials: Development of protein coated nanoceria as a potential antioxidative nano-agent for the effective scavenging of reactive oxygen species in vitro and in zebrafish model. Colloids and Surfaces B: Biointerfaces, 2016, 146, 375–386

  14. S. Uday Kumar and P.Gopinath*. Field-actuated Antineoplastic Potential of Smart and Versatile PEO-bPEI Electrospun Scaffold by Multi-staged Targeted Co-delivery of Magnetite Nanoparticles and Niclosamide-bPEI Complexes. RSC Advances, 2016,6,46186-46201

  15. K.Navaneetha Pandiyaraj, P.V.A.Padmanabhan, A.Arun, M.C.RamKumar, R.R.Deshmukh, Avi Bendavid, Pi-G Su, A.Sachdev, P.Gopinath. Cold atmospheric pressure (CAP) plasma assisted tailoring of LDPE film surfaces for enhancement of adhesive and cytocompatible properties: Influence of operating parameters. Vacuum, 2016, 130,34-47

  16. P.Dubey and P.Gopinath*. Nanocarriers for AKT siRNA based gene therapy. Austin Journal of Biotechnology & Bioengineering. 2016,(in press) Editorial

  17. S. Uday Kumar and P.Gopinath*. Nanotechnology- A Promising Approach for Suicide Gene Therapy. Austin Journal of Nanomedicine & Nanotechnology. 2016,(in press) Editorial

  18. B.Bhushan and P.Gopinath*. Nano-Enabled Approaches for Lung Cancer Therapy. Austin Journal of Lung Cancer Research. 2016,(in press) Editorial

  19. K.Navaneetha Pandiyaraj, A. Arun Kumar M.C.Ram Kumar, R.R.Deshmukh, Avi Bendavid , Pi-Guey Su, S.Uday Kumar, P.Gopinath. Effect of cold atmospheric pressure plasma gas composition on the surface and cyto-compatible properties of low density polyethylene (LDPE) film. Current Applied Physics, 2016, 16,784-792

  20. D. Malwal and P.Gopinath*. Enhanced photocatalytic activity of hierarchical three dimensional metal oxide@CuO nanostructures towards the degradation of Congo red dye under solar radiations. Catalysis Science & Technology , 2016,6, 4458-4472

  21. I. Matai and P.Gopinath*. Hydrophobic Myristic acid Modified PAMAM Dendrimers Augments the Delivery of Tamoxifen to Breast Cancer Cells. RSC Advances, 2016, 6,24808-24819

  22. K.N.Pandiyaraj, A.Arun Kumar, M.C.Ramkumar, A.Sachdev, P.Gopinath, Pieter Cools, N. De Geyter, R. Morent, R.R.Deshmukh, M.N. Nadagouda. Influence of non-thermal TiCl4/Ar+O2 plasma-assisted TiOx based coatings on the surface of polypropylene (PP) films for the tailoring of surface properties and cytocompatibility. Materials Science and Engineering C, 2016, 62, 908–918

  23. A. Sachdev, I. Matai and P.Gopinath*. Carbon Dots Incorporated Polymeric Hydrogels as Multifunctional Platform for Imaging and Induction of Apoptosis in Lung Cancer Cells. Colloids and Surfaces B: Biointerfaces, 2016, 141, 242–252 featured in ATLAS of Science

  24. A. Sachdev and P.Gopinath*. Monitoring the Intracellular Distribution and ROS Scavenging Potential of Carbon dots-Cerium oxide Nanocomposites in Fibroblast Cells. ChemNanoMat, 2016,2, 226–235

  25. I. Matai and P.Gopinath*. Chemically Crosslinked Hybrid Nanogels of Alginate and PAMAM Dendrimers as Efficient Anticancer Drug Delivery Vehicles. ACS Biomaterials Science & Engineering2016, 2,213–223

  26. P. Dubey and P.Gopinath*.Fabrication of electrospun poly (ethylene oxide)-poly (capro lactone) composite nanofibers for co-delivery of niclosamide and silver nanoparticles exhibits enhanced anti-cancer effects in vitro. Journal of Materials Chemistry B, 2016, 4, 726-742

  27. D. Malwal and P.Gopinath*. Fabrication and Applications of Ceramic nanofibers in Water Remediation: A review. Critical Reviews in Environmental Science and Technology, 2016,46, 500-534

  28. R. Manoj Kumar, K. K. Kuntal, S. Singh, P. Gupta, B. Bhushan, P. Gopinath and D. Lahiri. Electrophoretic deposition of hydroxyapatite coating on Mg–3Zn alloy for orthopaedic application. Surface and Coatings Technology, 2016,287,82–92

  29. S. Nayak, B. Bhushan, R. Jayaganthan, P. Gopinath, R.D. Agarwal and D.Lahiri. Strengthening of Mg based Alloy through Grain Refinement for Orthopedic Application. Journal of the Mechanical Behavior of Biomedical Materials,2016,59,57–70

  30. B. Bhushan and P.Gopinath*. Tumor-targeted folate-decorated albumin stabilised silver nanoparticle induce apoptosis at low concentration in human breast cancer cells. RSC Advances, 2015,5,86242-86253

  31. S. Uday Kumar and P.Gopinath*. Bioactive core-shell nanofiber hybrid scaffold for efficient suicide gene transfection and subsequent time resolved delivery of prodrug for anticancer therapy. ACS Applied Materials & Interfaces, 2015, 7, 18717–18731 (featured in “NATURE INDIA)

  32. I. Matai, A. Sachdev and P.Gopinath*. Self-assembled hybrids of fluorescent carbon dots and PAMAM dendrimers for epirubicin delivery and intracellular imaging. ACS Applied Materials & Interfaces, 2015,7,11423-11435

  33. P. Dubey, B. Bhushan, A. Sachdev, I. Matai, S. Uday Kumar and P.Gopinath*. Silver nanoparticles incorporated composite nanofiber for potential wound dressing applications. Journal of Applied Polymer Science, 2015132, 42473. (Cover page of the issue)

  34. P. Dubey, I. Matai, S. Uday Kumar, A. Sachdev, B. Bhushan and P.Gopinath*. Perturbation of cellular mechanistic system by silver nanoparticles toxicity: cytotoxic, genotoxic and epigenetic potential. Advances in Colloid and Interface Science, 2015, 221:4-21

  35. B. Bhushan and P.Gopinath*. Antioxidant nanozyme: A facile synthesis and evaluation of reactive oxygen species scavenging potential of nanoceria encapsulated albumin nanoparticles. Journal of Materials Chemistry B, 2015, 3, 4843-4852.

  36. S. Uday Kumar and P.Gopinath*. Controlled delivery of bPEI-niclosamide complexes by PEO nanofibers and evaluation of its anti-neoplastic potentials. Colloids and Surfaces B: Biointerfaces, 2015, 131:170-81.

  37. A. Sachdev and P.Gopinath*. Green synthesis of multifunctional carbon dots from coriander leaves and their potential application as antioxidants, sensors and bioimaging agents. Analyst, 2015, 140, 4260-4269.

  38. I. Matai, A. Sachdev and P.Gopinath*. Multicomponent 5-fluorouracil loaded PAMAM stabilized-silver nanocomposites synergistically induce apoptosis in human cancer cells. Biomaterials Science2015,3,457–468 (Cover page of the issue)

  39. A.Sachdev, I.Matai and P.Gopinath*. Dual-functional carbon dots-silver@zinc oxide nanocomposite: In vitro evaluation of cellular uptake and apoptosis induction. Journal of Materials Chemistry B, 2015,3,1208–1220 (Cover page of the issue)

  40. B. Bhushan, P. Dubey, S. Uday Kumar, A. Sachdev, I. Matai and P.Gopinath*. Bionanotherapeutics: Niclosamide Encapsulated Albumin Nanoparticles as a Novel Drug Delivery System for Cancer Therapy. RSC Advances, 2015,5,12078–12086 

  41. D. Malwal and P.Gopinath*. Fabrication and characterization of poly (ethylene oxide) templated nickel oxide nanofibers for dye degradation. Environmental Science: Nano, 2015,2,78–85

  42. S. Uday Kumar, I. Matai, P. Dubey, B. Bhushan, A. Sachdev and P.Gopinath*. Differentially cross-linkable core-shell nanofibers for tunable delivery of anticancer drugs: Synthesis, characterization and its anticancer efficacy. RSC Advances 2014, 4, 38263–38272.

  43. B. Bhushan, S. Uday Kumar, I. Matai, A. Sachdev, P.Dubey and P. Gopinath*,Ferritin Nanocages: A Novel Platform for Biomedical Applications.Journal of Biomedical Nanotechnology 2014,10,2950-2976.

  44. A. Sachdev, I. Matai and   P. Gopinath*. Implications of surface passivation on physicochemical and bioimaging properties of carbon dots. RSC Advances, 2014, 4,20915-20921.

  45. I. Matai, A. Sachdev, P. Dubey, S. Uday Kumar, B. Bhushan and P. Gopinath*, Antibacterial Activity and Mechanism of Ag-ZnO Nanocomposite on S.aureus and GFP-expressing Antibiotic Resistant E.coli. Colloids and Surfaces B: Biointerfaces 2014,115, 359–367.

  46. G. Bhargavi, I. Matai, A. Sachdev, S. Uday Kumar and P. Gopinath*,Microwave Assisted Synthesis of Chitosan Nanorods and Assessment of its Antibacterial Activity against GFP-Expressing Antibiotic Resistant E. coli. Journal of Chitin and Chitosan Science, 2013, 1, 1–6.

  47. A. Sachdev, I. Matai, S.Uday Kumar, B.Bhushan, P. Dubey and   P. Gopinath*. A novel one-step synthesis of PEG passivated multicolour fluorescent carbon dots for potential biolabeling application. RSC Advances, 2013, 3, 16958-16961.

  48. Sukumar UK, Bhushan B, Dubey P, Matai I, Sachdev A and P.Gopinath*. Emerging applications of nanoparticles for lung cancer diagnosis and therapy. International Nano Letters,2013, 3:45

  49. G. Sahni, P. Gopinath and P. Jeevanandam. A Novel Thermal Decomposition Approach to Synthesize Hydroxyapatite-Silver Nanocomposites and their Antibacterial Action against GFP-expressing Antibiotic Resistant E.coli. Colloids and Surfaces B: Biointerfaces  2013,Volume 103, Pages 441–447

  50. N. Kaur, N. Choudhary, R.N. Goyal ,S. Viladkar , I. Matai , P. Gopinath, S. Chockalingam ,D. Kaur. Magnetron sputtered Cu3N/NiTiCu shape memory thin film heterostructures for MEMS applications. Journal of Nanoparticle Research 2013,15:1468.

  51. V.K. Yata, P.Gopinath and S.S.Ghosh, Emerging Implications of Nonmammalian Cytosine Deaminases on Cancer Therapeutics. Applied Biochemistry and Biotechnology, 2012, 167(7):2103-16.

  52. P. Gopinath, S.K. Gogoi, P.Sanpui, A. Paul, A. Chattopadhyay  and S.S. Ghosh, Signaling Gene Cascade in Silver Nanoparticle Induced Apoptosis, Colloids and Surfaces B: Biointerfaces, 2010 Jun 1;77(2):240-5.

  53. Roman J, Rangasamy T, Guo J, Sugunan S, Meednu N, Gopinath Packirisamy, Shimoda L, Golding A,Semenza G and Georas SN, T Cell Activation Under Hypoxic Conditions Enhances Interferon-gamma Secretion, American Journal of Respiratory Cell and Molecular Biology ,2010, 42, 123-128.

  54. P. Gopinath and S.S.Ghosh, Understanding Apoptotic Signaling Pathways in Cytosine Deaminase-Uracil Phosphoribosyl Transferase Mediated Suicide Gene Therapy in vitro, Molecular and Cellular Biochemistry, 2009, 324, 21-29.

  55. P. Gopinath, S.K. Gogoi, A. Chattopadhyay  and S.S. Ghosh, Implications of Silver Nanoparticle Induced Cell Apoptosis for in vitro Gene Therapy, Nanotechnology , 2008, 19 (7).

  56. P. Gopinath and S.S.Ghosh, Implication of functional activity for determining therapeutic efficacy of suicide genes in vitro, Biotechnology Letters , 2008, 30, 1913-1921.

  57. P. Gopinath and S.S.Ghosh, Apoptotic Induction with Bifunctional E. coli Cytosine Deaminase- Uracil Phosphoribosyltransferase Mediated Suicide Gene Therapy Is Synergized By Curcumin Treatment in vitro, Molecular Biotechnology  , 2008, 39, 39-48.

  58. P. Gopinath and S.S. Ghosh, Monitoring green fluorescent protein for functional delivery of E. coli cytosine deaminase suicide gene and the effect of curcumin in vitro, Gene Therapy and Molecular Biology , 2007, 11, 219-228.

  59. S.K. Gogoi, P. Gopinath, A. Paul, A. Ramesh, S.S. Ghosh, and A. Chattopadhyay, Green Fluorescent Protein Expressing Escherichia coli as a model system for investigating the Antimicrobial activities of Silver Nanoparticles, Langmuir, 2006, 22, 9322-9328.

  60. S.S. Ghosh, P. Gopinath, and A. Ramesh, Adenoviral Vectors: A promising tool for Gene therapy, Applied Biochemistry and Biotechnology, 2006, 133 (1), 9-29.