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Ghosh Kaushik
Ghosh, Kaushik Associate Professor ghoshfcy[at]iitr.ac.in +91-1332-285547
Areas of Interest
  • Inorganic Chemistry, Bioinorganic and organometallic chemistry
  • Coordination chemistry, Metal complexes and their interactions with DNA and proteins
  • Inorganic Biochemistry, Catalysis, Organometallic Chemistry
Professional Background
FromToDesignationOrganisation
20012002Post-doctoral ResearcherMagnetic Resonance Centre, University of Florence, Italy
20022005Post-doctoral ResearcherUniversity of California, Santa Cruz, USA
20062012Assistant ProfessorDepartment of Chemistry, Indian Institute of Technology Roorkee, India
2012ongoingAssociate ProfessorIIT Roorkee
Honors and Awards
AwardInstituteYear
Certificate of Merit , First Class FirstUniversity of Kalyani1993
DST-SERC Fast Track Scheme for Young ScientistsDST New Delhi2007
Educational Details
DegreeSubjectUniversityYear
M.Sc.ChemistryIndian Institute of Technology Kanpur1996
B.Sc.Chemistry, Mathematics, PhysicsUnivesity of Kalyani1993
Ph.D.ChemistryIndian Association for the Cultivation of Science2001
Administrative Background
FromToDesignationOrganisationLevel
20062011MemberDepartmental Research Committee
20072008Faculty Advisor, Table TennisIIT Roorkee
2011ongoingMemberDepartmental Academic Committee
2009ongoingExam CoordinatorChemistry Department
Sponsored Research Projects
TopicFunding AgencyYear
Studies on Manganese Peptide InteractionDST New Delhi2008
Synthesis and characterization of ruthenium complexes and their DNA binding studiesCSIR2008
Participation in seminars
NamePlaceSponsored ByDate
MTIC XIIIIT MadrasDST6-8th Dec
Memberships
  • CRSI, INDIA, Life member
  • DNA Society of India, Life member
Teaching Engagements
TitleCourse CodeClass NameSemester
Chemistry of Main Group and Transition ElementsCY-512P.G.(including Pre Phd Course)Spring
Advance Inorganic Chemistry - IICY-622(I)P.G.(including Pre Phd Course)Spring
Advanced Coordination ChemistryCY-631P.G.(including Pre Phd Course)Autumn
Basic Inorganic ChemistryCY-202MU.G.Autumn
Chemistry Common CourseCY101U.G.Autumn
Quantum mech and Chemical BondingCY-511P.G.(including Pre Phd Course)Autumn
Chemistry Common CourseCY-101U.G.Spring
Research Scholar Groups
Scholar NameInterest
Ashish K. DharaBioinorganic chemistry of copper
Ovender SinghCoordination chemistry
Anand RatanRuthenium chemistry
KiranCoordination Chemistry
Kapil KumarCoordination chemistry
Manju BalaCoordination chemistry
Ankur MajiCoordination chemistry
Anshu SinghCoordination chemistry
Sheela KumariCoordination chemistry
KDP Lakshmee KumarCatalysis
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Year
Studies on iron and manganese complexes of polydentate ligandsNidhi TyagiA1
Study on some cancer marker genes and their relation with herbal and synthetic anticancer moleculesAjanta ChakravortyA1
Studies on copper and zinc complexes of polydentate ligandsPramod KumarA1
Studies on ruthenium chemistrySushil KumarA1
Studies on chemistry of some polydentate ligands and their metal complexesVarun MohanA1
Benzothiazole derivatives for elctro-optical applicationsB.M.N.K. PrasadA1
Some aspects of manganese and iron chemistry with polydentate ligandsSweety RathiO1
Some aspects of chemistry of ruthenium with polydentate ligandsRajan KumarA1
Studies on some transition metal chelatesAsish K. DharaO1
Studies on coordination chemistry of iron and mangananese and their applicationsOvender SinghO1
organometallic chemistry of Pd and RuAnand RatanO2013
Special Lectures Delivered
TitlePlaceDate
Orthometallation and synthesis of ruthenium(III) organometallics: Reactions of nitric oxideInt Conv Centre Jeju KoreaNov6, 2013
Generation of phenoxyl radical complex: Protease and nuclease activitySalemFeb 2013
Synthesis of nitrosyl complexes: Controlled delivery of nitric oxidePondicheryMarch2014
Refereed Journal Papers

Publications:

  1. Stabilization of Mn(II) and Mn(III) in mononuclear complexes derived from tridentate ligands with N2O donors: Synthesis, crystal structure, superoxide dismutase activity and DNA interaction studies Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Udai P. Singh, Nidhi Goel, J. Inorg. Biochem. 2010, 104, 9-18.
  2. Role of carboxamido nitrogen in mononuclear manganese complex: Superoxide scavenging activity and nuclease activity Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Inorg. Chem. Commun. 2010, 13, 380-383.
  3. Synthesis and reactivity studies on new copper(II) complexes: DNA binding, generation of phenoxyl radical, SOD and nuclease activity Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Vaibhave Aggarawal, Maria Camilla Baratto, Eur. J. Med. Chem. 2010, 45, 3770-3779.
  4. Oxidative Cyclization of a Phenolic Schiff Base and Synthesis of a Cyclometalated Ruthenium Nitrosyl Complex: Photoinduced NO Release by Visible Light. Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh, Nidhi Goel, Inorg. Chem. 2010, 49, 7235–7237.
  5. Novel Diphenoxo-Bridged Dinuclear Zinc Complexes: Generation of Phenoxyl-Radical Species and Nuclease Activity Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Inorg. Chem. 2010, 49, 7614-16.
  6. Synthesis and characterization of a novel ruthenium nitrosyl complex and studies on photolability of coordinated NO Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Inorg. Chem. Commun. 2011, 14, 146-149.
  1. Synthesis, Structural Characterization and DNA Interaction Studies on a Novel Copper Complex: Nuclease Activity via Self−activation Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Nidhi Goel, Inorg. Chem. Commun. 2011, 14, 489-92.
  2. In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupium Ajanta Chakraborty, Neetu Gupta, Kaushik Ghosh, Partha Roy Toxicology in Vitro, 2010, 24, 1215-1228.
  3. Evaluation of a Schiff base copper complex compound as potent anticancer molecule with multiple targets of action   Ajanta Chakraborty, Pramod Kumar, Kaushik Ghosh, Partha Roy, European Journal of Pharmacology, 2010, 647, 1-12.
  4. Efficient nuclease activity of dinuclear iron(III) complex derived from dinucleating ligand having carboxamido nitrogen donors Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Udai P. Singh, Nidhi Goel Inorg. Chem. Commun. 2012, 20, 167-171.
  5. DNA interaction, superoxide scavenging and cytotoxicity studies on new copper(II) complexes derived from tridentate ligand Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Nidhi Goel, Ajanta Chakravorty, Partha Roy, Maria Camilla Baratto  Polyhedron, 2011, 30, 2667-2677.
  6. Photocleavage of Coordinated NO under Visible Light from two Different classes of Organometallic Ruthenium Nitrosyl Complexes: Reversible Binding of Phenolato Function Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh, Nidhi Goel  Organometallics, 2011, 30, 2498-2505.
  7. Synthesis, crystal structure and DNA interaction studies on mononuclear zinc complexes Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi Inorg. Chim. Acta 2011, 375, 77-83.
  8. Self-activated DNA cleavage and NO reactivity studies on mononuclear copper complexes Kaushik Ghosh, Pramod Kumar, Varun Mohan, Udai P. Singh Inorg. Chem. Commun., 2012, 15, 50-56.
  9. Ruthenium(III) Cyclometalates Obtained by Site-Specific Orthometallation and Their Reactivity with Nitric Oxide: Photoinduced Release and Estimation of NO Liberated from the Ruthenium Nitrosyl Complexes Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh Eur. J.  Inorg.  Chem. 2012, 929-938.
  10. Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway Ajanta Chakraborty, Naganjaneyulu Bodipati, Marija Krstic Demonacos, Ramakrishna Peddinti  Kaushik Ghosh  Partha Roy  Molecular and Cellular Endocrinology 2012, 355, 25-40.
  11. Synthesis and structures of mononuclear cobalt complexes derived from tridentate ligands: DNA Binding and Nuclease Activity Studies Kaushik Ghosh, Varun Mohan, Pramod Kumar, Udai P. Singh Polyhedron 2013,  49, 167- 176.
  12. Nuclease Activity via Self-Activation and Anticancer Activity of a Mononuclear Copper(II) Complex: Novel Role of the Tertiary Butyl Group in the Ligand Frame Kaushik Ghosh, Pramod Kumar, Varun Mohan, Udai P. Singh, Sahba Kasiri, and Subhrangsu S. Mandal  Inorg. Chem.201251,3343–3345.
  13. Donation and Scavenging of Nitric Oxide (NO) by Flipping of Denticity of Carboxylate Ligand in Novel Ruthenium Complexes: Photolability of Coordinated NO Kaushik Ghosh, Sushil Kumar, Rajan Kumar. Inorg. Chim. Acta 2013, 405, 24-30. 
  14. Synthesis and characterization of chromium(III) complexes derived from tridentate ligands: Generation of phenoxyl radical and catalytic oxidation of olefins Kaushik Ghosh, Pramod Kumar, Isha Goyal Inorg. Chem. Commun., 2012, 24, 81-86.
  15. Synthesis, characterization and photochemical properties of some ruthenium nitrosyl complexes  A. Kumar, R. Pandey, R. K. Gupta, Kaushik Ghosh, D. S. Pandey Polyhedron2013, 52,  837-843.
  16. Syntheses, structures and properties of ruthenium complexes of tridentate ligands: isolation and characterization of a rare example of ruthenium nitrosyl complex containing {RuNO}5 moiety Kaushik Ghosh, Rajan Kumar, Sushil Kumar Dalton Trans, 2013, 42, 13444-52.
  17. Sensing of Fe(III) ion via turn-on fluorescence by fluorescence probes derived from 1-naphthylamine Kaushik Ghosh, S. Rathi, R.Khuswaha Tetrahedron  Letters, 2013, 54, 6460-63.
  18. Ruthenium(II) complexes derived from the ligands having carboxamide groups: Reactivity and scavenging of nitric oxide (NO) Kaushik Ghosh, S. Kumar, R. Kumar, U. P. Singh  J. Orgmet. Chem., 2014, ASAP article.

  19. Synthesis, structure, redox properties and DNA interaction studies of mononuclear iron(III) complexes with amidate ligand Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Udai P. Singh Inorg. Chim. Acta, 2014, ASAP article.