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Nath Mala (Ms)
Mala Nath Professor malanfcy[at] 91-01332-285797 Website
Areas of Interest
  • Organotin/organosilicon chemistry, Organotin-based anti-cancer compounds and their mode of action
  • Organotin chemistry, Organotin compounds as precursors for nanosized sem-conducting SnO2
  • Metal-organic frameworks, Metal-organic based Materials of multi-functional utility
Professional Background
Honors and Awards
Two Gold medals for Ist position in M.Sc.Lucknow university, Lucknow1976
one Gold medal for Ist position in B.Sc.Navyug Kanya Vidyalaya, Lucknow University1974
Educational Details
B.Sc.Chemistry, Botany, Zoology with Ist Position Lucknow University, Lucknow 1974
B.Sc. HonsInorganic Chemistry with 2nd positionLucknow University, Lucknow 1975
M.Sc.Inorganic Chemistry with Ist positionLucknow University, Lucknow 1976
Ph.D.Organotellurium ChemistryLucknow University, Lucknow 1980
Administrative Background
20082010Member of library committeeIITR
20062008Departmental representative of research comitteeIITR
20152017Chairperson, DAPCDepartment of Chemistry
2016till datePresiding OfficerInternal Complaints Committee
20082010Coordinator for ChemistryIIT Mandi
20132013Chairperson of M.Tech. admissionIITR
20142014Chairperson of M.Tech. admissionat IITR
20152015Chairperson of M.Tech. AdmissionIITR
20162016Chairperson, M.Tech. AdmissionIITRoorkee
20022010Member of Professorial committee of Biotechnology DepartmentIITRoorkee
Sponsored Research Projects
TopicFunding AgencyYear
Organotin(IV) Carboxylates and their mixed Ligands Comds. as Chemotherapeutics and their mechanismDBT2018
NMR Structural and Biophysical Studies on binding of anthraquinone derivatives with Guanine-QuadruplDBT, New Delhi2017
QSAR and solution studies of organotin- peptides/nucleotidesDepartment of Science and Technology, New Delhi2005
Hydrogen storage using activated carbon based materials incorporated with metal-organic compoundsMHRD2011
Synthesis, structural and biological activity of organotin compoundsCouncil of Science & Technology, U.P., Lucknow2002
New organotin derivatives of amino acids and peptides:Synthesis,characterization, antitumor activityUGC1998
Extraction and determination of Mo, Pd and Pt by using Schiff basesUniversity grants commission2004
Synthesis,structural and biological studies on organometallic compounds ofSi, Sn and Pb of S-ligandsCSIR1994
Studies on Reactivity of metal and organometal complexesof Schiff Bases of amino acidsCouncil of Science & Technology, U.P., Lucknow1989
Role of transition metals in chemical evolutionDST, New Delhi1990
Participation in seminars
NamePlaceSponsored ByDate
Seminar on Organometallic Chemistry (dedicated to Late Prof. T. N. Srivastava)Lucknow UniversityLucknow University/ DST New Delhi30.3.2010
  • American Chemical Society, Member
  • National Science Congress, Life member
  • National Academy of Sciences India, Allahabad , Member
  • National Academy of Sciences India, Dehradun , Member
  • Indian Chemical Society, Kolcutta, Life member
Teaching Engagements
TitleCourse CodeClass NameSemester
General Chemistry-IICY-006B.Tech. First YearSpring
Advanced Coordination Chemistry (New revised ccourse in 2016)CYN-509M.Sc. First YearAutumn
Chemistry for B. Tech. I YrCYN-008B.Tech. I YrSpring
Organometallic chemistry and Inorganic rings, chains and clustersCYN-502M.Sc. Spring
Solid state chemistry and its applicationsCYN-611M.Sc. Autumn
PracticalsCYN-511M.Sc. Autumn
Advanced Coordination Chemistry Revised courseCYN-509M.Sc. Autumn
Common ChemistryCy-101B.Tech. First YearAutumn
Advanced Laboratory-ICY-561M.Sc. First Year + Intg. M.Sc. IV YearAutumn
Advanced Coordination ChemistryCYN-509M.Sc. First Yr. + Intg. M.Sc. IV Yr,Autumn
Advanced Laboratory-ICYN-511M.Sc. First Yr. + Intg. M.Sc. IV Yr,Autumn
Advanced Organometallic ChemistryCYN-502M.Sc. First Yr. + Intg. M.Sc. IV Yr,Spring
Basic Inorganic ChemistryCy-512M.Sc. First Year +Intg. M. Sc. IV YearSpring
Coordination Chemistry (old no:CY-551)CYN-509M.Sc. First Year + Intg. M.Sc. IV YearAutumn
Advanced Coordination and Organometallic ChemistryCY-512M.Sc. First Year + Intg. M.Sc. IV YearSpring
Advanced Coordination Chemistry (old course)CY-631M.Sc.Second YearAutumn
LAB ICY-551M.Sc. First Year + Intg. M.Sc. IV YearAutumn
LAB IICY-542M.Sc. First Year + Intg. M.Sc. IV YearSpring
Solid-state Chemistry and its applicationCY-643M.Sc.Second Year + Intg. M.Sc. V YearAutumn
Advanced Inorganic Chemistry (I)CY-622(I)M.Sc.Second YearSpring
Advanced Inorganic Chemistry ICY-622M.Sc.Second YearSpring
Specialised PracticalsCY-641M.Sc.Second YearAutumn
Solid State Chemistry and its applicationsCYN-622(I)M.Sc. Second Year + Intg. M.Sc. V Yr.Autumn
Projects and Thesis Supervised
Title of ProjectNames of Students
Preparation and characterization of carbonaceous materials incorporatedwith organometallic compoundsSh. Asheesh Kumar
Studies on Organosilicon(IV) Derivatives of Schiff Bases Ms. Deepti Arora
Organosilicon Derivatives of Oxygen and Nitrogen Donor LigandsSh. Sanjay Kumar Maurya
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Year
Interaction of Organotin(IV) moities with DrugMs. RanjanaO2013
Organotin(IV) Complexes of Macromolecular N-DonorsSh. Sundeep KumarA2011
Speciation, Cytotoxic and DNA Binding Studies of Organotin(IV) CarboxylatesMs. MridulaA2010
Interaction of Organotin(IV) Moities with DNA and Nucleic Acid ConstitutentsMs. Nagamani KompelliA2009
Organotin(IV) Carboxylates: Potential Anti-tumor and Anti-inflammatory Agents Ms. Monika VatsA2007
Stabilization of Cubic Spinel Li-Mn-O by Dopants,As Cathode Material in Li-ion BatteryMs. Priti Singh A2006
Organotin(IV) Derivatives of Schiff Bases andMacrocyclesSh. Permendra Singh SainiA2003
Organotin(IV) Derivatives of Peptides andNucleotides.Sh. Hitendra SinghA2002
Organotin Derivatives of Some Heterocyclic LigandsMs. SulaxnaA2001
Studies on Novel Organotin(IV) Derivatives of PeptidesSh. Sandeep PokhariaA1999
Interaction of Organotin(IV) Compounds with Biologically Important LigandsMs. Ruchi JairathA2000
Studies on Organosilicon(IV) Derivatives ofAmino AcidsMs. Sunita GoyalA1996
Studies on Organotin(IV) Derivatives of Amino Acids and DipeptidesMs. Rakesh YadavA1995
Preparation and Characterization of Some Rare-Earth(III)-Iron(III) Mixed OxidesMs. Nidhi BhartiA1992
Studies of Organotin(IV) Complexes of ThioSchiff BasesMs. Savita GoyalA1990
Role of Ferrocyanide in Chemical Evolution Ms. Archana SharmaA1987
Physiochemical Studies of Organotin Schiff Bases ComplexesMs. Neelam SharmaA1987
Chemical Evolution of Transition metal (Fe, Zn) contg. Enzymes Ms. S. W. DeopuzariA1984
Metal-Organic Frame works as Adsorbents and PhotocatalystsRamesh ChandraO2014
Metal Sulphide Nanoparticles@Metal-organic Frameworks: As PhotocatalystSh. Ankur MallickO2015
Metal Oxides/Sulphides base Nano Composites and their ApplicationsPooja BhatiaO2016
Organotin complexes as catalysts in organic synthesisShubhamO2017
Organotin derivatives of O- and N- donors as green catalysts and PVC stabilizersVinod YadavA2018
Visits to outside institutions
Institute VisitedPurpose of VisitDate
NIT Uttarakhand, Srinagar1. To frame Chemistry courses (02) for B. Tech. I and II year students and Pre-Ph. D. courses (04) in Chemistry. 2.Invited Guest Lecture on “Cancer Chemotherapy: Challenges and Future Perspectives of Metal Based Drugs” followed by the interactive session with the research scholars of Chemistry Department of NIT Uttarakhand.17.2.2018
Punjab University, Chandigargh, IndiaDelivered an invited lecture on "Developments of Organotin Compounds as Chemotherapeutic Agents: Challenges and Future prospects" in Achievements of Women in Science and Technology: Current Scenario and Future Prospects-2017, held on 13-14 Jan.,2017 at Punjab University, Chandigargh, India.13.1.2017
-To present a research paper entitled 'Core-Shell Based SnO2NPs@ZIF-8Compositeas an Effective Photo-catalystfor Degradation of Methylene Blue in Wastewater Treatment' in 9th International Conference on Materials for Advanced Technologies (ICMAT-2017) at Suntec, Singapore. 18-23 June
-To present a research paper, entitled 'Temperature Cntrolled Single Phase TiO2 (Anatase/Rutile) Nanoparticles by Using Metal-Organic Compounds as Precursors in 11th Asian Thermophysical Properties Conference, ATPC-2016, HELD ON 2-6 October, 2016 at Yokohama, Japan.2-10-2016
University of Exeter, UKAttended and presented a paper entitled, "Production of Semicon-ductors Nanometric Particles of SnO2 and SnS from Organo-tin(IV) Triazolates as Precursors", in "International Conference on Condensed Matter and Materials Physics (Symposia on Nano-structured Materials)", University of Exeter, London. 20.4.2006
-To present a research paper, entitled 'Metal-based Anticancer Agents: In Vitro DNA Binding, Cleavage and Cytotoxicity' in International Conference on Metallurgy, Materials Science and Engineering: ICMMSE-2014 held on 14-15 August 2014 at NH Laguna Palace, Vale Ancona 2 30172, Mestre, Venezia, Italy. 14.8.2014
University of Mauritius, Mauritius1. Delivered a plenary lecture on "Developments in Organotin-based Anti-tumor Compounds" in International Conference on Pure and Applied Chemistry. 2. Attended and Presented a research paper entitled, "Spectral Characterization and Anticancer Screening of Triorganotin(IV) Carboxylates", in International Conference on Pure and Applied Chemistry. 3. Chaired a session also in the same conference.26.7.2010
University of LucknowDelivered an Invited Lecture on, “Developments and Mode of Action of Organotin-based Anti-Cancer Compounds” in International Conference & Humboldt Kolleg on “ Recent Aspects of Organic/ Organometallic Compounds and their Usefulness in Materials and Industries", organized by Lucknow University and Alexander von Humboldt Foundation, Germany. 3-6.1.2012
University of MexicoAttended and Presented a research paper entitled, "Microporous Carbonaceous Materials Incorporated with Metal (TI, V and Zn) for Hydrogen Storage" in ", XXI International Materials Reasearch Congress (XXI IMRC)".12.8.2012
NIT HamirpurTo conduct Ph. D. Viva-voce24/09/2015
University of LucknowDelivered an Invited Lecture on, “Organotin(IV) Compounds: Anti-cancer and Anti-inflammatory Agents”in a Seminar organized on ‘Organometallic Chemistry’ (dedicated to Late Prof. T. N. Srivastava). 31.3.2010
" Developments of Organotin Compounds as Chemotherapeutic Agents: Challenges and Future Prospects" (In: Achievements of Women in Science and Technology: Current Scenario and Future Prospects)-2017Punjab University, Chandigarh, IndiaT2017
Developments in Organotin-based Anti-cancer CompoundsUniversity of Mauritius (in: International Conference on Pure and Applied Chemistry (ICPAC-2010)) T2010
Organotin(IV) Compounds: Anti-cancer and Anti-inflammatory AgentsLucknow University (Seminar on ‘Organometallic Chemistry')T2010
Developments and Mode of Action of Organotin-based Anti-Cancer CompoundsLucknow University (in:International Conference “ Recent Aspects of organometallics")T2012
To design the syllabii of Pre-Ph.D. courses of chemistry department and B.Tech I and II Yr. Chemistry Courses (2018)NIT, Srinagar, GarhwalI2018
Challenges and Future Prospects of Metal-based Drugs in Cancer Chemotherapy (2018)NIT Srinagar, GarhwalG2018
Courses or Conferences Organised
Conference NameSponsored ByDate
Gender Sensitization and Sexual Harassment of Women at WorkplaceIIT Roorkee14.6.2018
Special Lectures Delivered
International Conference on Pure and Applied Chemistry.Maurtius30.7.2010
Cancer Chemotherapy: Challenges and Future Perspectives of Metal Based DrugsNIT Uttarakhand, Srinagar17.2.2018
Organotin(IV) Compounds: Anti-cancer and Anti-inflammatory AgentsLucknow University, Lucknow31.3.2010
Books Authored

1. Inorganic Chemistry: A Laboratory Manual, Published by Narosa Publishing House Pvt. Ltd., New Delhi,  India, 2016.

2. Book Chapter, entitled "The Cardiovascular Activity of Organotin Compounds" in:Tin Chemistry, Fundamentals, Frontiers, and Applications, Eds.: A.G. Davies, M. Gielen, K.H. Pannell, E.R.T. Tiekink, Published by Wiley, A John Wiley and Sons, Ltd, Publication,2008.

Refereed Journal Papers

1. Multifunctional CdSNPs@ZIF-8: Potential Antibacterial Agent against GFP-Expressing Escherichia coli and Staphylococcus aureus and Efficient Photocatalyst for Degradation of Methylene Blue, A. Malik, Mala Nath, S. Mohiyuddin and G. Packirisamy, ACS Omega, 3 (2018) 8288-8308.

2Structure-cytotoxicity Relationship for Apoptotic Inducers Organotin(IV) Derivatives of Mandelic Acid and L-Proline and their Mixed Ligand Complexes having Enhanced Cytotoxicity, Mala Nath, P. Roy, R Mishra and M. ThakurAppl. Organomet. Chem. (2018), e4663; DOI: 10.1002/aoc.4663.

3. New diorganotin(IV) complexes of salicylaldehyde based hydrazones bearing furan heterocycle moiety:X-ray structural investigation of dimethyltin(IV) and diphenyl-tin(IV) complexes.Sundeep Kumar and Mala Nath, J. Organomet. Chem., 856 (2018) 87-99.

4.Synthesis, Characterization and Binding Studies of Novel Diorganotin(IV) Complexes of Sodium 2-mercaptoethane-sulfonate. Ranjana Kumari and Mala Nath*, Appl. Organomet. Chem. (2018), DOI: 10.1002/aoc.4365.

5. Synthesis and Characterization of Novel Trimethyltin(IV) and Tributylltin(IV) Complexes of Anticoagulant, WARFARIN: Potential DNA Binding and Plasmid Cleaving Agents, R. Kumari and Mala Nath, Inorg. Chem. Commun., 95 (2018) 40-46.

6. Tri- and diorganotin(IV) derivatives of non-steroidal anti-inflammatory  drug, Sulindac: Characterization, electronic structures (DFT), DNA binding, and plasmid cleavage studies. Ranjana Kumari and Mala Nath*, Appl. Organomet. Chem. (2017),       doi/10.1002/aoc.e- 3661.

7. Novel Binuclear diorganotin(IV) complexes of adipic acid dihydrazone containing  flexible aliphatic spacer: X-ray structural characterization of dimethyltin(IV) complex.Sundeep Kumar and Mala Nath, J. Organomet. Chem., 853 (2017) 113-121.

8.Microwave–assisted synthesis of mixed ligands organotin(IV) complexes of 1,10-phenanthroline and L-proline: physicochemical characterization, DFT calculations,chemotherapeutic potential validation by in vitro DNA binding and nuclease activity. Mala Nath*, Mridula and Ranjana Kumari, J. Photochem. Photobiol. B: Biology, 174 (2017) 182-194.

9. New triphenyltin(IV) complexes of flexible tripodal Schiff base ligands: X-ray structural characterization of Ph3SnCl. (H3trensal). Sundeep Kumar and Mala Nath, J. Organomet. Chem., 848 (2017) 10-21. 

10.Multi-Core–shell TiO2NPs@ZIF-8 Composite for Enhanced Photocatalytic Degradation and Adsorption of Methylene Blue and Rhodamine-B,R. Chandra, Mala NathChem. Select., 2 (2017) 7711-7722.

11. TiO2@ZIF-8: A Novel Approach of Modifying Micro-environment for Enhanced Photo-catalytic Dye Ddegradation and High Usability of TiO2 Nanoparticles. R. Chandra, S. Mukhopadhyay, M. Nath, Mat. Lett. `164 (2016) 571-574.

12. Conventional and Microwave–assisted Synthesis, Characterization, DFT Calcula-tions, in vitro DNA Binding and Cleavage Studies of Potential Chemotherapeutic Diorganotin(IV) Mandelates. Mridula and Mala Nath*, J. Photochem. Photobiol. B: Biology, 162 (2016) 348-360.

13. Mode of Action of Tin-based Anti-proliferative Agents: Biological Studies of Organotin(IV) Derivatives of Fatty Acids, M. Nath  M. Vats, P. Roy, J. Photo-chem. Pho-tobiol. B: Biology, 148 (2015) 88-100.

14. Tri- and diorganotin(IV) complexes of biologically important orotic acid: Synthesis,spectroscopic studies, in vitro anti-cancer, DNA fragmentation, enzyme assays and in vivo anti-inflammatory activities, M. Nath , M. Vats  and P. Roy, Eur. J. of Med. Chem., 59 (2013) 310-321.

15. Chemistry and applications of organotin(IV) complexes of Schiff bases. Perspective, M. Nath and P. K. Saini, Dalton Trans 40 (2011), 7077-7121.

16.. Design and Microwave-assisted Synthesis of Tri- and Dialkyltin(IV) Hippurates, Characterization, In Vitro Anti-cancer and In Vivo Anti-inflammatory Activities, M. Nath, M. Vats, P. Roy, Med. Chem. Res.,24 (2015) 51-62.

17.. Design, Spectral Characterization, Anti-tumor and Anti-inflammatory Activity of Triorganotin(IV) Hydroxyl-carboxylates, Apoptosis Inducers: In Vitro Assessment of Induction of Apoptosis by Enzyme, DNA-fragmentation, Acridine Orange and Comet Assays,M. NathM. Vats, P. Roy, Inorg. Chim. Acta, 423 (2014) 70-82.

18..New di- and triorganotin(IV) complexes of tripodal Schiff base ligand containing three imidazole arms: Synthesis, structural characterization, biological activity and thermal studies, M. Nath, P. K. Saini and A. Kumar, J. Organomet. Chem., 695 (2010), 1353–1362.

19. Organotin(IV)tryptophanylglycinates: Potential Non-Steroidal Anti-inflammatory  Agents; Crystal Structure of Dibutyltin(IV) tryptophanylglycinate, M. Nath, H. Singh, P. Kumar, A. Kumar, X. Song and G. Eng, Appl. Organomet. Chem., 23 (2009), 347-358.

20.. New Triorganotin(IV) Derivatives of Dipeptides as Anti-inflammatory Anti-microbial Agents, M. Nath S.  Pokharia,  G.  Eng,  X.  Song, and  A. Kumar,  Eur.  J.  Med. Chem., 40(3), (2005), 289-298.

21Preparation and Characterization of Li[Mn2-xFex]O4 (x = 0.0-0.6) Spinel Nanoparticles as Cathode Materials for Lithium Ion Battery, P. Singh, A. Sil, M. Nath, S. Ray, Adv. Mater. Res., 67 (2009) 233-238.

  • 1. Laboratory Manual for B.Tech. I Yr Course, CYN-006, CYN-008 Under QIP program of 2013-2014. 2. Laboratory Manual for M. Sc. I Yr Course, CYN-551, CYN-510 Under QIP program of 2014-2015., 1. Design the practicals of B.Tech. I Yr, Revised courses CYN-006, CYN-008 in such a way to impart the practical training of various important aspects of chemistry to complete it with in 2 hr of practical class. 2. Teaching the students through power point with suitable graphics software to show actual 3d- structure to the students. 3. Assignments at postgraduate level have been designed to cover the format/types of questions asked in GATE/CSIR-UGC NET examinations., 1. The students are asked to solve the assignments in the class. 2. The students do/practice the problems based on GATE/CSIR-UGC NET in class.