Partha Roy
Professor
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Interests
Animal Biotechnology, Molecular Endocrinology, Mechanism of hormone actions, Stem Cell Biology, Cancer Biology and therapeutics, Tissue Engineering
partha.roy@bt.iitr.ac.in
--
91-01332-285686
Biosketch
Educational Details
Professional Background
Administrative Positions

Research
Projects
Papers
Books
Collaborations

Honours and Awards
Honors
Memberships

Teaching Engagements
Teaching Engagements

Students
Supervisions
Associate Scholars

Miscellaneous
Events
Visits
Miscellaneous
BioSketch
Educational Details
University of Kalyani
1990
B.Sc., Zoology (H); Botany, Chemistry
University of Kalyani
1993
M.Sc., Zoology (Spl. Endocrinology & Reproductive Physiology)
Visva Bharati University
1997
Ph.D., Life Sciences (Zoology)
Professional Background
Research Associate
01 Jan 1997 - 01 Jan 1998
Chonnam National University, Republic of Korea
Research Associate
01 Jan 1998 - 01 Jan 2000
Institute of Biomedicine, University of Turku, Finland
Research Scientist
01 Jan 2001 - 01 Jan 2001
Glenmark Research Center, Glenmark Pharmaceuticals Pvt. Ltd. Mubai, India
Research Associate
01 Jan 2001 - 01 Jan 2003
Institute of Reproductive and Developmental Biology, Imperial College London, UK
Assistant Professor
01 Jan 2004 - 01 Jan 2009
Indian Institute of Technology Roorkee
Visiting Faculty
01 Jan 2010 - 01 Jan 2010
School of Biological Sciences and Technology, Chonnam National University, South Korea
Visiting Faculty
01 Jan 2012 - 01 Jan 2012
Department of Physiology, Institute of Biomedicine, University of Turku, Finland
Visiting Faculty
01 Jan 2015 - 01 Jan 2015
University of Aberdeen, Scotland, UK
Administrative Positions
Head, Department of Biotechnology
01 Jan 2015 - 01 Jan 2018
Indian Institute of Technology Roorkee
Chairman, Institute Bio-safety Committee
01 Jan 2017 - 01 Jan 2019
Indian Institute of Technology Roorkee
Research
Projects
TOPIC START DATE FIELD DESCRIPTION FINANCIAL OUTLAY FUNDING AGENCY OTHER OFFICERS
Innovations for Rural & Societal Development using Traditional Medicinal and Aromatic Plants based p 01 Jan 2019 Innovations for Rural & Societal Development using Traditional Medicinal and Aromatic Plants based p 74.33 Lakhs Department of Biotechnology, Govt. of India Prof. Vinay Sharma, Prof. Rajat Agrwawal
Assessment of the mechanism of actions of some selected Homeopathic preparation for their role in th 01 Jan 2018 Assessment of the mechanism of actions of some selected Homeopathic preparation for their role in th 40.53 Lakhs Ministry of AYUSH, Government of India Prof. D. Sircar
Organotin(IV) carboxylates and their mixed ligands compounds as potential chemotherapeutics and stud 01 Jan 2018 Organotin(IV) carboxylates and their mixed ligands compounds as potential chemotherapeutics and stud 46.44 Lakhs Department of Biotechnology, Govt. of India Prof. mala Nath
In vitro (cell based) characterization of some synthetic drugs for anti-cancer/other activities 01 Jan 2018 In vitro (cell based) characterization of some synthetic drugs for anti-cancer/other activities 27.97 Lakhs Michigan Diagonistics Pvt. Ltd, Michigan, USA Prof. D. Sircar; Porf. M. R. Maurya
Development of a rapid and robust high throughput reporter cell based bioassay for the detection of 01 Jan 2018 Development of a rapid and robust high throughput reporter cell based bioassay for the detection of 62.01 Lakhs National Agricultural Science Fund (NASF), Govt. of India Prof. D. Sircar




Honors And Awards
Honors
Chonnam National University
2010
"Brain Pool Program Fellowship" offered by Korean Federation of Science and Technology Societies
Society for Reproductive Biology and Comparative Endocrinology India
2012
Fellow in Reproduction and Endocrinology (FRE)
Department of Physiology, Institute of Biomedicine, University of Turku
2012
Visiting Professorship offered by Academy of Finland
Indian Institute of Technology Roorkee
2014
Outstanding Teacher’s Award – 2014
University of Aberdeen, Scotlan, UK
2015
"Visiting Faculty" by INSA – Royal Society, Edinburgh, Exchange of Scientist Program
Indian Institute of Technology Roorkee
2016
Ramkumar Outstanding Teaching and Research Award – 2016
Indian Institute of Technology Roorkee
2019
Outstanding Teacher’s Award – 2019
MemberShips
Society for Reproductive Biology and Comparative Endocrinology, India
04 Aug 2020 - Present
Fellow
Society for Biological Chemists, India
04 Aug 2020 - Present
Life Member
Asia Oceania Society for Comparative Endocrinology
04 Aug 2020 - Present
Life Member
Society of Ethnopharmacology, India
04 Aug 2020 - Present
Life Member
International Society of Nutraceuticals & Chronic Diseases
04 Aug 2020 - Present
Life Member
Students
SuperVisions
Screening and biological characterization of some natural/ synthetic endocrine disruptors
01 Jan 2004 - Present
Other Supervisors: , Scholar: Dr. Vikas Kumar
Studies on anti-diabetic active principles from plants and mechanism of action.
01 Jan 2004 - Present
Other Supervisors: Prof. C. B. Majumder, Scholar: Dr. Bhawna Sharma
Development of bioassays for endocrine disruptors and study their mode of action.
01 Jan 2005 - Present
Other Supervisors: Prof. C. B. Majumder, Scholar: Dr. Gunda Vishwanath
Investigation of pharmacological profile of some endocrine disruptors in male rats.
04 Aug 2020 - Present
Other Supervisors: , Scholar: Dr. Sharad Sharma
Development of yeast based steroid bioassay for screening some natural endocrine disruptors
01 Jan 2005 - Present
Other Supervisors: Prof. C. B. Majumder, Scholar: Dr. Shamba Chatterjee
Screening and Biological Characterization of a Synthetic and Natural Anticancer molecule
01 Jan 2006 - Present
Other Supervisors: Prof. Kaushik Ghosh, Scholar: Dr. Ajanta Chakraborty
Studies on Fe and Zn bioavailability, regulation of hepcidin and its role in glucose homeostasis
01 Jan 2007 - Present
Other Supervisors: , Scholar: Dr. Rajani Salunke
Organitin (IV) carboxylates: Potential anti-tumor and anti-inflammatory agents.
01 Jan 2008 - Present
Other Supervisors: Prof. Mala Nath, Scholar: Dr. Monika Vats
Assessment of various factors regulating osteoblast differentiation of stem cells
01 Jan 2009 - Present
Other Supervisors: , Scholar: Dr. Swati Srivastava
Biological evaluation of a novel Pterostilbene-derivative as potent anticancer agent
01 Jan 2010 - Present
Other Supervisors: , Scholar: Dr. Kumar Nikhil
Endocrine modulating activities of some environmental and industrial chemicals
01 Jan 2010 - Present
Other Supervisors: , Scholar: Dr. Narender Kumar
Endocrine disrupting action of tributyltin in reproductive and metabolic functions
01 Jan 2011 - Present
Other Supervisors: , Scholar: Dr. Shruti Sharan
Effects of some flavonoids on obesity-linked type 2 diabetes: Role of autophagy
01 Jan 2012 - Present
Other Supervisors: , Scholar: Dr. Ritu Varshney
Understanding the mechanism of differentiation of stem cells towards osteoblastic and neuronal linea
01 Jan 2014 - Present
Other Supervisors: , Scholar: Ms. Rutusmita Mishra
Development of biosensors for detecting metabolites in urine samples related to diseases.
01 Jan 2014 - Present
Other Supervisors: , Scholar: Mr. Somesh banerjee
Plant based medicines for the cure and management of cancer
01 Jan 2015 - Present
Other Supervisors: , Scholar: Mr. Neeladrisingha Das
Cellular spheroids and their usage in the screening of anti-cancer drugs
01 Jan 2016 - Present
Other Supervisors: , Scholar: Ms. Parul Katiyar
Development of cells based reporter assays to analyze bioavailable micronutrients (iron and zinc) fr
01 Jan 2016 - Present
Other Supervisors: , Scholar: Mr. Sandeep Nathani
Analyzing the role of pterostilbene and its derivatives in preventing breast cancer induced metastas
01 Jan 2016 - Present
Other Supervisors: , Scholar: Mr. Vinay Kumar
Understanding the role of various factors in the neural regeneration processes
01 Jan 2017 - Present
Other Supervisors: Prof. Debrupa Lahiri, Scholar: Mr. Souvik Ghosh
Analyzing the role of some polyherbal formulations for the cure and management of neurodegenerative
01 Jan 2018 - Present
Other Supervisors: , Scholar: Ms. Saakshi Saini
Assessment of the role of some medicinal plants for the cure of diabetes and other metabolic disorde
01 Jan 2018 - Present
Other Supervisors: Prof. D. Sircar, Scholar: Mr. Chandrachur Ghosh
Miscellaneous
Books Authored

1. W. Jacob, P. Roy and B. M. J. Pereira. Estrogen receptor: signaling and crosstalk. In: Maitra SK, ed. Hormone Biotechnology, First Edition. Daya Publishing House, New Delhi, 2006: 161-178 (ISBN: 817035451X, 9788170354512).

 2. V. Kumar, B. M. J. Pereira and P. Roy. Endocrine disruptors: their mechanism of actions and testing strategies to assess human hazard. In: Maitra SK, ed. Hormone Biotechnology, First Edition. Daya Publishing House, New Delhi, 2006: 357-369 (ISBN: 817035451X, 9788170354512).

 3. G. Viswanath, V. Pundeer, B.M.J. Pereira, Partha RoyDevelopment of recombinant cell based multi-tiered assays for screening endocrine disrupting chemicals and determination of androgen bioactivity in human serum. In: Dutta – Gupta A and Senthilkumaran B, eds. Frontiers in Molecular Endocrinology of Invertebrates and Vertebrates, Volume II, First Edition. University of Hyderabad, Hyderabad, 2006: 55-60.

4. B. Sharma, S. Chatterjee, Partha Roy. Identification of a non-functional luteinizing hormone receptor in Ishikawa cells. In: Dutta – Gupta A and Senthilkumaran B, eds. Frontiers in Molecular Endocrinology of Invertebrates and Vertebrates, Volume II, First Edition. University of Hyderabad, Hyderabad, 2006: 61-64.

5. Anil Kumar, Sonu Ambwani, Partha Roy (2008). Techniques in Animal Cell Culture. G. B. Pant University of Agriculture & Technology Press. First Edition (2008).

6. Mala Nath, Monika Vats, Partha Roy. Synthesis, Spectral Characterization and Anticancer Screening of Triorganotin(IV) Carboxylates. In: Bhowon MG, Laulloo SJ and, Wah HLK and Ramasami P, ed. Chemistry for Sustainable Development. First Edition. Springer, 2012: 301-315 (DOI 10.1007/978-90-481-8650-1, e-ISBN 978-90-481- 8650-1).

7. Swati Srivastava, Partha Roy. Stem Cell Technology. In: Kumar A, Pareek A, Gupta SM, ed. Biotechnology in Medicine and Agriculture. First Edition. I. K. International Publishing House Pvt. Ltd. 2013: 664-687 (ISBN: 978-93-81141-40-3).

8. Swati Haldar, Debrupa Lahiri, Partha Roy. 3D Print Technology for Cell Culturing (Chapter 5). In Ahmed Nabeel, Gopinath P, Datta Rajib, eds. 3D Printing  Technology in Nanomedicine. First Edition. Elsevier Inc. 2019: 83-114 (ISBN: 978-0-12-815890-6).

9. Ritu Varshney, Rutusmita Mishra, Neeladrisingha Das, Partha Roy. Structure-Function Elucidation of Flavonoids by Modern Technologies: Role in Management of Diabetes and Cancer (Chapter 3). In Ghosh Dilip and Mukherjee Pulok K, ed. Natural Medicines: Clinical Efficacy, Safety and Quality. First Edition. CRC Press (Taylor Francis). 2019: 25-63 (ISBN 9781138733060).

Refereed Journal Papers

1.  S. Halder, P. Roy, A. Chatterjee and S. Bhattacharya (1995): Bioactive forms of       gonadotropin releasing hormone in the brain of an Indian major carp, Catla catla (Ham). Journal of Biosciences 20(4):551-561.

2. A. Bandyopadhyay, P. Roy and S. Bhattacharya (1996): Thyroid hormone induces the synthesis of a putative protein in rat granulosa cell which stimulates progesterone release. Journal of Endocrinology 150: 309-318.

3.  B. Mukhopadhyay, P. Roy, A. Chatterjee and S. Bhattacharya (1997): Intracellular    events in response to GnRH causing gonadotropin release from the pituitary cells of a channidae fish, Channa punctatus, Bloch. Comparative Biochemistry and Physiology 118C 2: 129-136.

4.  M. Datta, P. Roy and S. Bhattacharya (1998): Thyroid hormone induces the progesterone release from human corpus luteum by the synthesis of a putative protein. Journal of Endocrinology 158(3): 319-325.

5. P. Roy, A, Chatterjee, P. P. Banerjee and S. Bhattacharya (2000): A thyrptropin like molecule from the pituitary of an Indian fresh water murrel: Comparison of its biological activity with other thyrotropins. Comparative Biochemistry and Physiology C (Pharmacology and Toxicology) 125(2): 165-177.

6. P. Roy, M. Datta, S. Dasgupta and S. Bhattacharya (2000): GnRH stimulates thyroid activity in a fresh water murrel, Channa gachua (ham) and carps, Catla catla (ham) and Cirrhinus mrigala (ham). General and Comparative Endocrinology 117(3): 456-463. 

7. P. R. Manna, P. Roy, B. Clarck, D. M. Stocco and I. T. Huhtaniemi (2001): Interaction of Thyroid hormone and steroidogenic acute regulatory protein in the regulation of murine Leydig cell steroidogenesis. Journal of Steroid Biochemistry and Molecular Biology 76 (1-5): 167-77.

8. P. Roy, H. Salminen, P. Koskimies, J. Simola, A. Smeds, P. Saukko and I. Huhtaniemi (2004) Screening of some antiandrogenic endocrine disruptors using a recombinant cell based in vitro bioassay. Journal of Steroid Biochemistry and Molecular Biology 88: 157-166.

9. P. Roy and B. M. J. Pereira (2005) A treatise on the hazards of endocrine disruptors and tools to evaluate them. Indian Journal of Experimental Biology 43: 975-992.

10. P. Roy, S. Franks, M. S. Read and I Huhtaniemi (2006) Determination of androgen bioactivity in human serum samples using a recombinant cell based in vitro bioassay. Journal of Steroid Biochemistry and Molecular Biology 101: 68-77.

11. Rahul, C.B. Majumder and P. Roy (2006) Single drop Microextraction-Gas Chromatography Mass Spectrometry: A method for determination of organophosphorus pesticides in fruit juices and water. Research Journal of Chemistry and Environment 10(4): 5-12.

12. Shamba Chatterjee, Chandrajeet B. Majumder and Partha Roy (2007) Development of a yeast based assay to determine the (anti)androgenic contaminants from pulp and paper mill effluents in India Environmental Toxicology and Pharmacology 24: 114-121.

13. G. Vishawanath, S. Chatterjee, P. Roy (2007) Assessment of luteinizing hormone receptor function in an endometrial cancer cell line, Ishikawa cells in response to human chorionic gonadotrophic hormone. Molecular and Cellular Endocrinology 272: 14-21.

14. Mesala Lavanya, Chandrajeet Balomajumder, Shamba Chatterjee and Partha Roy (2008). Biodesulfurization of dibenzothiophene using recombinant Pseudomonas strain. Journal of Chemical Technology and Biotechnology 83(3): 294-298.

15. Vikas Kumar, Ajanta Chakraborty, Gunda Viswanath and Partha Roy (2008). Androgenic endocrine disruptors in wastewater treatment plant effluents in India: their influence on reproductive processes and systemic toxicity in male rats. Toxicology and Applied Pharmacology 226: 60-73.

16. P. Roy, M. Alevizaki, and I. Huhtaniemi (2008). In vitro bioassays for androgens and their diagnostic applications. Human Reproduction Update 14(1): 73-82.

17. Shamba Chatterjee, Vikas Kumar, Chandrajeet B. Majumder, Partha Roy (2008). Screening of some anti-progestin endocrine disruptors using a recombinant yeast-based in vitro bioassay. Toxicology In Vitro 22: 788-798.

18. Bhavna Sharma, G. Viswanath, Rajni Salunke and Partha Roy (2008). Effects of flavonoid rich extract from seeds of Eugenia jambolana (L.) on carbohydrate and lipid metabolism in diabetic mice. Food Chemistry 110: 697-705.

19. Anil K Mathur, C. B. Majumder, Shamba Chatterjee, Partha Roy (2008). Biodegradation of pyridine by the new bacterial isolates S. putrefaciens and B. sphaericus. Journal of Hazardous Materials 157: 335-343.

20. B. Sharma, C. B. Majumder and P. Roy (2008). Assessment of hypoglycemic and hypolipidemic effect of flavonoid rich extract from Eugenia jambolana (L.)  seeds on streptozotocin induced diabetic rats. Food and Chemical Toxicology 46: 2376-2383.

21. Vikas Kumar, Chandrajeet Balomajumder and Partha Roy (2008). Effects of endocrine disrupting chemicals from leather industry effluents on male reproductive system. Journal of Steroid Biochemistry and Molecular Biology 111: 208-216.

22. Vikas Kumar, Chandrajeet Balomajumder and Partha Roy (2008). Disruption of LH induced testosterone biosynthesis in testicular Leydig cells by Triclosan: probable mechanism of action.  Toxicology 250:124-131.

23. Vikas Kumar, Mool Raj Kural, B.M.J. Pereira and Partha Roy (2008). Spearmint induced hypothalamic oxidative stress and testicular anti-androgenicity in male rats - altered levels of gene expression, enzymes and hormones. Food and Chemical Toxicology 46: 3563-3570.

24. Gunda Viswanath, Sujata Halder, Gunda Divya, Chandrajeet B Majumder, Partha Roy (2008). Detection of potential progesterogenic endocrine disruptors using a recombinant human progesterone receptor binding assay and transactivation bioassay. Molecular and Cellular Endocrinology 295: 1-9.

25. Sham M. Sondhi, Reshma Rani, Partha Roy, S. K. Agarwal and S. K. Saxena (2009). Microwave assisted synthesis of N-substituted cyclic imides and their evaluation for anticancer and anti-inflammatory activities. Bioorganic and Medicinal Chemistry Letters 19: 1534-1538.

26. Vikas Kumar, Ajanta Chakraborty, Mool Raj Kural, Partha Roy (2009). Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan. Reproductive Toxicology 27: 177-185.

27. Bhavna Sharma, Rajani Salunke, Swati Srivastava, Chandrajeetbalo Majumder, Partha Roy (2009). Effects of guggulsterone isolated from Commiphora mukul in high fat diet induced diabetic rats. Food and Chemical Toxicology 47: 2631-2639.

28. Bhavna Sharma, Rajani Salunke, Chandrajeetbalo Majumder, Supriya Daniel, Partha Roy (2010). Anti-diabetic potential of alkaloid rich fraction from Capparis decidua plants on diabetic mice. Journal of Ethnopharmacology 127: 457-462.

29. Sham M. Sondhi, Reshma Rani, Partha Roy, S. K. Agrawal, A. K. Saxena (2010). Conventional and microwave assisted synthesis of small molecule based biologically active heterocyclic amidine derivatives. European Journal of Medicinal Chemistry 45: 902-908.

30. Sham M. Sondhi, Reshma rani, Jaiveer Singh, Partha Roy, S. K. Agrawal, A. K. Saxena (2010). Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives. Bioorganic and Medicinal Chemistry Letters 20: 2306-2310.

31. Gunda Viswanath, Shamba Chatterjee, Swati Dabral, Siddharth R Nanguneri, Gunda Divya, Partha Roy (2010). Anti-androgenic endocrine disrupting activities of chlorpyrifos and piperophos. Journal of Steroid Biochemistry and Molecular Biology 120: 22-29.

32. Ajanta Chakraborty, Neetu Gupta, Kaushik Ghosh, Partha Roy (2010). In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupium. Toxicology in Vitro 24: 1215-1228.

33. Ajanta Chakraborty, Shamba Chatterjee, Partha Roy (2010). Progesterone receptor agonists and antagonists as anticancer agent. Mini Reviews in Medicinal Chemistry 10(6): 506-517.

34. Ajanta Chakraborty, Pramod Kumar, Kaushik Ghosh, Partha Roy (2010). Evaluation of a Schiff base copper complex compound as potent anticancer molecule with multiple targets of action. European Journal of Pharmacology 647: 1-12.

35. Rajani Salunke, Kumari Neelam, Nidhi Rawat, Vijay Kumar Tiwari, Gursharn S Randhawa, Harcharan Singh Dhaliwal, Partha Roy (2011). Bioavailability of iron from wheat Aegilops derivatives selected for high grain iron and protein contents. Journal of Agricultural and Food Chemistry 59(13): 7465-7473.

36. Rajani Salunke, Bhavna Sharma, Ketan Sarf, Partha Roy (2011). Smokeless tobacco extract impairs iron homeostasis in rats and human hepatoma, HepG2 cells. Toxicological and Environmental Chemistry 93(5): 1028-1044.

37. Sham M Sondhi, Jaiveer Singh, Partha Roy, S. K. Agrawal, A. K. Saxena (2011). Conventional and microwave-assisted synthesis of imidazole and guanidine derivatives and their biological evaluation. Medicinal Chemistry Research 20: 887-897.

38. Bhavna Sharma, Rajani Salunke, Santosh Satapati, Chandrajeet Balomajumder, Partha Roy (2011). Screening of some Indian medicinal plant extracts for their anti-hyperglycemic activities in streptozotocin induced diabetic mice. Journal of Food Biochemistry 35: 1398-1406.

39. Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P Singh, Nidhi Goel, Ajanta Chakraborty, Partha Roy, Maria C Baratto (2011). DNA interaction, super oxide scavenging and cytotoxicity studies on new Copper (II) complexes derived from tridentate ligand. Polyhedron 30(16): 2667-2677.

40. Sham M. Sondhi, Surbhi Arya, Reshma Rani, Nikhil Kumar, Partha Roy (2012). Synthesis, anti-inflammatory and anticancer activity evaluation of some mono- and bis-Schiff’s bases. Medicinal Chemistry Research 21: 3620-3628.

41. Swati Srivastava, Ajanta Chakraborty, Rajani Salunke, Partha Roy (2012). Development of a novel Polygalacturonic acid- Gelatin blend scaffold fabrication and biocompatibility studies for tissue-engineering applications. International Journal of Polymeric Materials 61: 1-20.

42. Ajanta Chakraborty, Naganjaneyulu Bodipati, Marija Krstic Demonacos, Ramakrishna Peddinti, Kaushik Ghosh, Partha Roy (2012). Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway. Molecular and Cellular Endocrinology 355(1): 25-40.

43. Sham M. Sondhi, Sandeep Kumar, Nikhil Kumar, Partha Roy (2012). Synthesis of anti-inflammatory and anticancer anticancer activity evaluation of some pyrazole and oxadiazole derivatives. Medicinal Chemistry Research 21: 3043-3052.

44. Swati Srivastava, Upasana Bedi, Partha Roy (2012). Synergistic actions of insulin-sensitive and Sirt1-mediated pathways in the differentiation of mouse embryonic stem cells to osteoblast. Molecular and Cellular Endocrinology 361: 153-164.

45. Rajani Salunke, Nidhi Rawat, Vijay Kumar Tiwari, Kumari Neelam, Gursharn Singh Randhawa, Harcharan Singh Dhaliwal, Partha Roy (2012). Determination of bioavailable-zinc from biofortified wheat using a coupled in vitro digestion/Caco-2 reporter-gene based assay. Journal of Food Composition and Analysis 25: 149-159.

46. Sham M Sondhi, Surbhi Arya, Reshma Rani, Nikhil Kumar, Partha Roy (2012). Synthesis, anti-inflammatory and anticancer activity evaluation of some mono- and bis-Schiff’s bases. Medicinal Chemistry Research 21: 3620-3628.

47. Surbhi Arya, Nikhil Kumar, Partha Roy, S. M. Sondhi (2012). Synthesis of amide and bis amide derivatives and their evaluation for anti-inflammatory and anticancer activity. European Journal of Medicinal Chemistry 59: 7-14.

48. Mala Nath, Monika Vats, Partha Roy (2013). Tri- and diorganotin(IV) complexes of biologically important orotic acid: Synthesis, spectroscopic studies, in vitro anti-cancer, DNA fragmentation, enzyme assays and in vivo anti-inflammatory activities. European Journal of Medicinal Chemistry 59: 310-321.

49. Swati Srivastava, Narender Kumar, Rajani Salunke Thakur, Partha Roy (2013). Role of Vanadium pentaoxide in the differentiation of C3H10t1/2 cells towards osteoblast lineage: A comparative analysis with other trace elements. Biological Trace Element Research 152(1): 135-142.

50. Swati Srivastava, Rohini Bankar, Partha Roy (2013). Assessment of the role of flavonoids for inducing osteoblast differentiation in isolated mouse bone marrow derived mesenchymal stem cells. Phytomedicine 20: 683-690.

51. Shruti Sharan, Kumar Nikhil, Partha Roy (2013). Effects of low dose treatment of tributyltin on the regulation of estrogen

52. Nargish Parvin, Tapas K Mandal, Partha Roy (2013). Polyelectrolyte Carbon Quantum-Dots: New Player as a Noninvasive Imaging Probe in Drosophila. Journal of Nanoscience and Nanotechnology 13: 6499-6505.

53. Kumud Kant Awasthi, Anjali Awasthi, Narender Kumar, Partha Roy, Kamalendra Awasthi, P. J. John (2013). Silver nanoparticle induced cytotoxicity, oxidative stress and DNA damage in CHO cells. Journal of Nanoparticle Research 15(1898): 1-12.

54. Govinda Kapusetti, Raghvendra Raman Mishra, Swati Srivastava, Nira Misra, Vakil Singh, Partha Roy, Santhosh Kumar Singh, Chanchal Chakraborty, Sudip Malik, Pralay Maiti (2013). Layered double hydroxide induced advancement in joint prosthesis using bone cement: The effect of metal substitution. Journal of Materials Chemistry B 1: 2275-2288.

55. Kumar Nikhil, Shruti Sharan, Ajanta Chakraborty, Naganjaneyulu Bodipati, Rama Krishna Peddinti, Partha Roy (2014). Role of isothiocyanate conjugate of pterostilbene on the inhibition of MCF-7 cell proliferation and tumor growth in Ehrlich ascitic cell induced tumor bearing mice. Experimental Cell Research 320: 311-328.

56. Swati Srivastava, Narender Kumar, Partha Roy (2014). Role of ERK/NFκB in vanadium (IV) oxide mediated osteoblast differentiation in C3H10t1/2 cells. Biochimie 101: 132-144.

57. Kumar Nikhil, Shruti Sharan, Ajanta Chakraborty, Partha Roy (2014). Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status. PLoS ONE 9(4): e93335. doi:10.1371/journal.pone.0093335.

58. Rajani Salunke, Nidhi Rawat, Kumari Neelam, Vijay Kumar Tiwari, Gursharn Singh Randhawa, Harcharan Singh Dhaliwal, Partha Roy (2014). Effect of grain hardness on bioavailability of iron in wheat as determined using the coupled invitro digestion/Caco-2 model. LWT - Food Science and Technology 59: 433-438.

59. Tomar PP, Nikhil K, Singh A, Selvakumar P, Roy P, Sharma AK (2014). Characterization of anticancer, DNase and antifungal activity of pumpkin 2S albumin. Biochemical Biophysical Research Communication 448(4): 349-354.

60. Narender Kumar, Shruti Sharan, Swati Srivastava , Partha Roy (2014). Assessment of estrogenic potential of diethyl phthalate in female reproductive system: involvement of ERK1/2 signalling pathway in regulation of aromatase. Reproductive Toxicology 49: 12-26.

61. Ravikumar Muppalla, Swati Srivastava, Partha Roy, Suresh K. Jewrajka (2014). Effect of atom transfer radical polymerization macroinitiator on properties of poly(meth)acrylate-based pentablock type of thermoplastic elastomers. Polymer 206:  155–165.

62. Kumar Nikhil, Shruti Sharan, Abhimanyu K. Singh, Ajanta Chakraborty, Partha Roy (2014). Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: Involvement of PPAR-γ. PLoS One  9(8): e104592. doi:10.1371/journal.pone.0104592.

63. Shruti Sharan, Kumar Nikhil, Partha Roy (2014). Disruption of thyroid hormone functions by low dose exposure of tributyltin: An in vitro and in vivo approach. General and Comparative Endocrinology 206: 155–165.

64. Sandeep Kumar, Nikhil Kumar, Partha Roy, Sham M Sondhi (2014). Efficient synthesis of heterocyclic compounds derived from 2,6-dioxopiperazine derivatives and their evaluation for anti-inflammatory and anticancer activities. Medicinal Chemistry Research 23: 3953-3969.

65. Swati Srivastava, Kirti Sharma, Narender Kumar, Partha Roy (2014). Bradykinin regulates osteoblast differentiation by Akt/ERK/NFkB signaling axis. Journal of Cellular Physiology 229(12): 2088-2105.

66. P. Trivedi, P. Gupta, S. Srivastava, R. Jayaganthan, R. Chandra, P. Roy (2014). Characterization and in vitro biocompatibility study of Ti-Si-N nanocomposite coatings developed by using physical vapor deposition. Applied Surface Science 293: 143 – 150.

67. Narender Kumar, Swati Srivastava, Partha Roy (2015). The impact of low molecular weight phthalates in inducing reproductive malfunctions of male mice: special emphasis on Sertoli cell functions. General and Comparative Endocrinology 215: 36–50.

68. Sanjay Singh, R. Manoj Kumar, Kishor Kumar Kuntal, Pallavi Gupta, Snehasish Das, R. Jayaganathan,  Partha  Roy, Debrupa  Lahiri (2015). Sol–Gel derived hydroxyapatite coating on Mg-3Zn alloy for orthopedic application. The Journal of The Minerals, Metals & Materials Society (JOM) 67(4): 702-712.

69. Kumud Kant Awasthi, Anjali Awasthi, Rajbala Verma, Narender Kumar, Partha Roy, Kamlendra Awasthic, P. J. John (2015). Cytotoxicity, genotoxicity and alteration of cellular antioxidant enzymes in silver nanoparticles exposed CHO cells. RSC Advances 5: 34927-34935.

70. Dinesh K. Patel, Dipak Rana, Vinod K. Aswal, Swati Srivastava, Partha Roy, Pralay Maiti (2015). Influence of graphene on self-assembly of polyurethane and evaluation of its biomedical properties. Polymer 65: 183-192.

71. Surbhi Arya, Anuj Kumar, Nikhil Kumar, Partha Roy, S. M. Sondhi. Synthesis and anticancer activity evaluation of some acridine derivatives (2015). Medicinal Chemistry Research 24: 1942-1951.

72. Anuj Kumar, Nikhil Kumar, Partha Roy, S. M. Sondhi, Anuj Sharma (2015). Synthesis of acridinecyclic imide hybrid molecules and their evaluation for anticancer activity. Medicinal Chemistry Research 24: 3272–3282. DOI 0.1007/s00044-015-1380-2.

73. Kumar Nikhil, Shruti Sharan, Srinivasa Rao Palla, Sham M. Sondhi, Rama Krishna Peddinti, Partha Roy (2015). Understanding the mode of action of a pterostilbene derivative as anti-inflammatory agent. International Immunopharmacology 28: 10 – 21.

74. Monika, Sanjeev Kumar Mahto, Snehashish Das, Amit Ranjan, Santosh Kumar Singh, Partha Roy, Nira Misra (2015). Chemical modification of poly(vinyl chloride) for blood and cellular biocompatibility. RSC Advances 5: 45231–45238.

75. Kumar Nikhil, Shruti Sharan, Partha Roy (2015). A pterostilbene derivative suppresses osteoclastogenesis by regulating RANKL-mediated NFkB and MAPK signaling in RAW264.7 cells. Pharmacological Reports 67: 1264–1272.

76. Pallavi Gupta, Shruti Sharan, Partha Roy, Debrupa Lahiri (2015). Aligned carbon nanotube reinforced polymeric scaffolds with electrical cues for neural tissue regeneration. Carbon 95: 715-724.

77. P Trivedi, S Goel, S Das, R Jayaganthan, D Lahiri, P Roy (2015). Biocompatibility of ultrafine grained zircaloy-2 produced by cryorolling for medical applications. Materials Science and Engineering: C 46: 309-315.

78. Mala Nath, Monika Vats, Partha Roy (2015). Mode of action of tin-based anti-proliferative agents: Biological studies of organotin(IV) derivatives of fatty acids. Journal of Photochemistry and Photobiology B: Biology 148: 88-100.

79. Narender Kumar, Swati Srivastava, Malgorzata Burek, Carola Y. Forster, Partha Roy (2016). Assessment of estradiol-induced gene regulation and proliferation in an immortalized mouse immature Sertoli cell line. Life Sciences 148: 268–278.

80. Kumar Nikhil, Shruti Sharan, Rohan Wishard, Srinivasa Rao Palla, Rama Krishna Peddinti, Partha Roy (2016). Pterostilbene carboxaldehyde thiosemicarbazone, a resveratrol derivative inhibits 17β-Estradiol induced cell migration and proliferation in HUVECs. Steroids 108: 17–30.

81. Vijayesh Kumar, Kumar Nikhil, Partha Roy, Debrupa Lahiri, Indranil Lahiri (2016). Emergence of fluorescence in boron nitride nanoflakes and its application in bioimaging. RSC Advances 6: 48025-48032.

82. Sumit Kumar, Nishant Verma, Nikhil Kumar, Alok Patel, Partha Roy, Vikas Pruthi, Naseem Ahmed (2016). Design, synthesis, molecular docking, and biological studies of novel phytoestrogen-tanaproget hybrids. Synthetic Communications 46(5): 460–474. 

83. Shubhrajyotsna Bhardwaj, Nirma Maurya, Ashok Kumar Singh, Ritu Varshney, Partha Roy (2016). Promising ESIPT-based fluorescence sensor for Cu2+ and CN- ions: investigation towards logic gate behaviour, anticancer activities and bioimaging application. RSC Advances 6: 102096–102101.

84. Anamika Singh, Narender Kumar, Prabhat P. S. Tomar, Sumit Bhose, Dilip Kumar Ghosh, Partha Roy, Ashwani K. Sharma (2017). Characterization of a bacterioferritin comigratory protein family 1-Cys peroxiredoxin from Candidatus Liberibacter asiaticus. Protoplasma 254:1675–1691.

85. Anuj Kumar, Somesh Banerjee, Partha Roy, S.M. Sondhi, Anuj Sharma (2017). Solvent free, catalyst free, microwave or grinding assisted synthesis of bis-cyclic imide derivatives and their evaluation for anticancer activity. Bioorganic & Medicinal Chemistry Letters 27: 501–504.

86. Ritu Varshney, Sumeet Gupta, Partha Roy (2017). Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/ mTOR signaling pathway. Molecular and Cellular Endocrinology 448: 1-20.

87. R. Manoj Kumar, Pallavi Gupta, Sandan Kumar Sharma, Akshat Mittal, Manish Shekhar,Vijayesh Kumar, B.V.Manoj Kumar, Partha Roy, Debrupa Lahiri (2017). Sustained drug release from surface modified UHMWPE for acetabular cup lining in total hip implant. Materials Science and Engineering C 77: 649-661.

88. S. Mohapatra, R. Mishra, P. Roy, K. L. Yadav, and S. Satapathi (2017). Systematic investigation and in vitro biocompatibility studies on implantable magnetic nanocomposites for hyperthermia treatment of osteoarthritic knee joints. Journal of Materials Science Biomaterials 52(16): 9262-9268.

89. Meenaxi Saini, Yogeshwar Masirkar, Ritu Varshney, Partha Roy, Kalyan K. Sadhu (2017). Fluorogen-free aggregation induced NIR emission Q1 Q2 from gold nanoparticles. Chemical Communications 53: 6199-6202.

90. Amol Sarkate, Somesh Banerjee, Javid Iqbal Mir, Partha Roy, Debabrata Sircar (2017). Antioxidant and cytotoxic activity of bioactive phenolic metabolites isolated from the yeast-extract treated cell culture of apple. Plant Cell Tissue and Organ Culture 130: 641–649.

91. Sonam Gupta, Ritu Varshney, Rajan Kumar Jha, Parul A. Pruthi, Partha Roy, Vikas Pruthi (2017). In vitro apoptosis induction in a human prostate cancer cell line by thermotolerant glycolipid from Bacillus licheniformis SV1. Journal of Surfactants and Detergents 20: 1141-1151

92. Neetu Singh, Udai P. Singh, Kumar Nikhil, Partha Roy, Hariji Singh (2017). Synthesis, structural, solubility and anticancer activity studies of salts using nucleobases and sulfonic acids conformer. Journal of Molecular Structure 1146: 703-712.

93. Poonam Kumari, Rutusmita Mishra, Neha Arora, Apurva Chatrath, Rashmi Gangwar, Partha Roy, Ramasare Prasad (2017). Antifungal and anti-biofilm activity of essential oil active components against Cryptococcus neoformans and Cryptococcus laurentii. Frontiers in Microbiology 8(2161): 1-14.

94. Preeti Verma, Bibekananda Kar, Ritu Varshney, Partha Roy, Ashwani K. Sharma (2017). Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis. The FEBS Journal 284(24): 4233-4261.

95. Rakesh Sharma, Govinda Kapusetti, Sayali Y Bhong, Partha Roy, Santosh Kumar Singh, Shikha Singh, Biswajit Ray, Pralay Maiti, Nira Misra (2017). Osteoconductive Amine Functionalized Graphene-Poly(methylmethacrylate) Bone Cement Composite with Controlled Exothermic Polymerization. ACS: Bioconjugate Chemistry 28(9): 2254-2265.

96. Ritu Varshney, Rajat Varshney, Rutusmita Mishra, Sumeet Gupta, Debabrata Sircar, Partha Roy (2018). Kaempferol alleviates palmitic acid-induced lipid stores, endoplasmic reticulum stress and pancreatic β-cell dysfunction through AMPK/mTOR-mediated lipophagy. Journal of Nutritional Biochemistry 57: 212-227.

97. Bahiru Tsegaye, Chandrajit Balomajumder, Partha Roy (2018). Biodegradation of wheat straw by Ochrobactrum oryzae BMP03 and Bacillus sp. BMP01 bacteria to enhance biofuel production by increasing total reducing sugars yield. Environmental Science and Pollution Research 25(30): 30585-30596. 

98. Amol Sarkate, Shashank Sagar Saini, Deepa Teotia, Mariam Gaid, Javid Iqbal Mir, Partha Roy, Pawan Kumar Agrawal, Debabrata Sircar (2018). Comparative metabolomics of scab-resistant and susceptible apple cell cultures in response to scab fungus elicitor treatment. Scientific Reports 8:17844. 

99. Archna Dhasmanaa, Lubhan Singh, Partha Roy, Narayan Chandra Mishra (2018). Silk fibroin protein modified acellular dermal matrix for tissue repairing and regeneration. Materials Science & Engineering C 97: 313-324.

100. Bahiru Tsegaye, Chandrajit Balomajumder, Partha Roy (2019). Isolation and characterization of novel lignolytic, cellulolytic, and hemicellulolytic bacteria from wood feeding termite Cryptotermes brevis. International Microbiology (Springer) 22: 29 - 39.

101. Bahiru Tsegayea, Chandrajit Balomajumder, Partha Roy (2019). Optimization of microwave and NaOH pretreatments of wheat straw for enhancing biofuel yield. Energy Conversion and Management 186: 82-92.

102. Ritu Varshney, Rutusmita Mishra, Neeladrisingha Das, Debabrata Sircar, Partha Roy (2019). A comparative analysis of various flavonoids in the regulation of obesity and diabetes: An in vitro and in vivo study. Journal of Functional Foods 59: 194-205.

103. Aniruddha Samanta, Soumik Podder, Murali Kumarasamy, Chandan Kumar Ghosh, Debrupa Lahiri, Partha Roy, Swarupananda Bhattacharjee, Jiten Ghosh, Anoop Kumar Mukhopadhyaya (2019). Au nanoparticle-decorated aragonite microdumbbells for enhanced antibacterial and anticancer activities. Materials Science and Engineering C 103: 109734-109763.

104. R. Manoj Kumar, Kanike Rajesh, Swati Haldar, Pallavi Gupta, K. Murali, Partha Roy, Debrupa Lahiria (2019). Surface modification of CNT reinforced UHMWPE composite for sustained drug delivery. Journal of Drug Delivery Science and Technology 52: 748-759.

105. S. Mokenapelli, M. Gutam, N. Vadiyaala, J. R., Yerrabelli, S. Banerjee, P. Roy, R. K. Kancha, B. R. Kunduru, S. R. Sagurthi, P. R. Chitneni (2019). Synthesis and cytotoxicity of novel 14α-O-(1,4-disubstituted-1,2,3-triazolyl) ester derivatives of andrographolide. Natural Product Research 20: 1 – 9.  https://doi.org/10.1080/14786419.2019.1628746

106. Harjeet Singh, Nikhil Shri Sahajpal, Harmanpreet Singh, Vanita Vanita, Partha Roy, Surinder Paul, Shashank Kumar Singh, Inderjit Kaur, Subheet Kumar Jain (2019). Pre-clinical and cellular toxicity evaluation of 7-methylxanthine: an investigational drug for the treatment of myopia. Drug and Chemical Toxicology 12: 1 - 10. https://doi.org/10.1080/01480545.2019.1635615

107. Nidhi Pal, Somesh Banerjee, Partha Roy, Kaushik Pal (2019). Reduced grapheme oxide and PEG-grafted TEMPO-oxidized cellulose nanocrystal reinforced poly-lactic acid nanocomposite film for biomedical application. Materials Science and Engineering C 104: 109956-109969.

108. Kapil Kumar, Ashish Kumar Dhara, Virendra Kumar Chaudhary, Nathani Sandip, Partha Roy, Pankaj Verma, Kaushik Ghosh (2019). The influence of the tertiarybutyl group in the ligand frame on the catalytic activities, DNA cleavage ability and cytotoxicity of dinuclearnickel(II) complexes. Inorganica Chimica Acta 495: 118993-119001.

109. Rutusmita Mishra, Ritu Varshney, Neeladrisingha Das, Debabrata Sircar, Partha Roy (2019). Synthesis and characterization of gelatin-PVP polymer composite scaffold for potential application in bone tissue engineering. European Polymer Journal 119: 155-168. doi.org/10.1016/j.eurpolymj.2019.07.007

110. Swati Haldar, Akriti Sharma, Sumeet Gupta, Samrat Chauhan, Partha Roy, Debrupa Lahiri (2019). Bioengineered smart trilayer skin tissue substitute for efficient deep wound healing. Materials Science & Engineering C 105: 110140 – 110151.

111. Swati Haldar, Souvik Ghosh, Viney Kumar,  Partha Roy, and Debrupa Lahiri (2019). The Evolving Neural Tissue Engineering Landscape of India. ACS Applied Bio Materials 2: 5446 – 5449.

112. Deepa Teotia, Mariam Gaid, Shashank S. Saini1, Aparna Verma, Ragothaman M. Yennamalli, Satyajeet P. Khare, Kiran Ambatipudi, Javid Iqbal Mir, Till Beuerle, Robert H€ansch, Partha Roy, Pawan Kumar Agrawal, Ludger Beerhues and Debabrata Sircar (2019). Cinnamate-CoA ligase is involved in biosynthesis of benzoate-derived biphenyl phytoalexin in Malus 3 domestica ‘Golden Delicious’ cell cultures. The Plant Journal 100: 1176- 1192.

113. Gourav Kumar,  Rashmi Gupta, Shruti Sharan, Partha Roy, Dev Mani Pandey (2019). Anticancer activity of plant leaves extract collected from a tribal region of India. 3 Biotech 9: 399 – 414.

114. Harmanpreet Singh, Sandip Nathani, Narpinder Singh, Partha Roy, Surinder Paul, Harminder Singh Sohale, Subheet Kumar Jain (2019). Development and characterization of Solid-SNEDDS formulation of DHA using hydrophilic carrier with improved shelf life, oxidative stability and therapeutic activity. Journal of Drug Delivery Science and Technology 54: 101326 – 101341.

115. Bahiru Tsegaye, Chandrajit Balomajumder, Partha Roy (2020). Organosolv pretreatments of rice straw followed by microbial hydrolysis for efficient biofuel production. Renewable Energy 148 (C): 923 – 934.

116. Kriti Juneja, Rutusmita Mishra, Samrat Chauhan, Sumeet Gupta, Partha Roy, Debabrata Sircar (2020). Metabolite profiling and wound-healing activity of Boerhavia diffusa leaf extracts using in vitro and in vivo models. Journal of Traditional and Complementary Medicine 10(1): 52-59.