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Naveen Kumar
Professor
naveen.navani[at]bt.iitr.ac.in
07088275555
Research Interests

Biosketch
Educational Details
Professional Background

Research
Projects
Publications
Patents
Books
Collaborations

Honours and Awards
Honors
Memberships

Teaching Engagements
Teaching Engagements

Students
Supervisions
Associate Scholars

Miscellaneous
Events
Visits
Administrative Positions
Miscellaneous
Research Interests
Molecular Biology, Synthetic Biology, Gene regulation, Microbial Biotechnology and Nanobiotechnology, Aptamers and MEMS nanodevices in Diagnostics, Probiotic recombinant enzymes, NanoBiotic Materials, Microbes' mediated bioremediation of polluted environments., Isolation and characterization of microbes from extreme and polluted environments.
BioSketch
Educational Details
McMaster University, Hamilton, Canada
2007
Post-Doctoral Research, Functional Nucleic acids/Molecular Biology
Institute of Microbial Technology (CSIR), Chandigarh
2002
Ph.D., Biotechnology/Molecular Biology
National Dairy Research Institute, Karnal
1993
M.Sc., Biotechnology
Professional Background
Scientist
01 Jan 1996 - 01 Jan 2003
National Bureau of Animal Genetic Resources (ICAR)
Research
Projects
TOPIC START DATE FIELD DESCRIPTION FINANCIAL OUTLAY FUNDING AGENCY OTHER OFFICERS
Mitigation of food borne pathogens using combination of natural food grade peptides decorated on nan 01 Jan 2019 Mitigation of food borne pathogens using combination of natural food grade peptides decorated on nan 49.7 lakhs MHRD-STARS -
Development of ready to go culture strips for fermented dairy products 01 Jan 2019 Development of ready to go culture strips for fermented dairy products 45.8 lakh INR BIRAC
A field survey of ethnic fermented food beverages of Uttarakhand 01 Jan 2019 A field survey of ethnic fermented food beverages of Uttarakhand 4.15 UCOST
Development of Nanoparticle based Aptasensor for detection of bacterial pathogens and xenobiotics in 01 Jan 2017 Development of Nanoparticle based Aptasensor for detection of bacterial pathogens and xenobiotics in 63.81 Lakh INR DBT
Detection and Control of Bacterial Pathogens in Poultry by Developing Chemical Genomic Strategies to 01 Jan 2017 Detection and Control of Bacterial Pathogens in Poultry by Developing Chemical Genomic Strategies to 104.36 lakh INR NASF-ICAR
Application of probiotic bacteria for enhancing nutritional status of underutilised millets of Uttar 01 Jan 2017 Application of probiotic bacteria for enhancing nutritional status of underutilised millets of Uttar 7.41 Lakh INR UCOST
Development of Nucleic acid aptamer based functional nanodevice strategies for sensing, capture and 01 Jan 2016 Development of Nucleic acid aptamer based functional nanodevice strategies for sensing, capture and 52.78 Lakh INR DST Nanomisssion
Value addition to the hill cattle of Uttarakhand using biotechnological investigation 01 Jan 2015 Value addition to the hill cattle of Uttarakhand using biotechnological investigation 15.73 Lakh UCOST -
Development of an Aptamer Biosensing system for Detection of water-borne Pathogen E.coli O157:H7 01 Jan 2012 Development of an Aptamer Biosensing system for Detection of water-borne Pathogen E.coli O157:H7 47 Lakh DBT, Govt of India
Detection and Mitigation of Dairy Pathogens and Detection of Adulterants using Chemical Biology 01 Jan 2009 Detection and Mitigation of Dairy Pathogens and Detection of Adulterants using Chemical Biology 695.73 lakhs INR Indian Council of Agricultural Research (ICAR), NAIP Dr Ranjana Pathania




Books

Edited Book series on Nanotechnology (1-10 Volumes).   (2013); Studium press LLC, USA.

  1. Vol.1: Fundamentals and Applications – Naveen Kumar Navani, Shishir Sinha and JN Govi
  2. Vol.2: Synthesis and Characterization- Shishir Sinha , Naveen Kumar Navani and JN Govil
  3. Vol.3: Properties of Nanomaterials - Shishir Sinha , Naveen Kumar Navani and JN Govil
  4. Vol.4: Nanomaterials and Nanostructures- Naveen Kumar Navani, Shishir Sinha and JN Govil
  5. Vol.5: Defence Applications Nanotechnology - Naveen Kumar Navani, Shishir Sinha and JN Govil
  6. Vol.6: Nanotechnology;Energy and Environment- Shishir Sinha , Naveen Kumar Navani and JN Govil
  7. Vol.7: Nanotechnology;Diagnostics and Therapeutics -- Naveen Kumar Navani, Shishir Sinha and JN Govil
  8. Vol.8: Nanotechnology;Electronics and Photovoltaics- Shishir Sinha , Naveen Kumar Navani and JN Govil
  9. Vol.9: Nanotechnology;Civil/ Construction Engineering- Shishir Sinha , Naveen Kumar Navani and JN Govil
  10. Vol.10: Nanosensing-- Naveen Kumar Navani, Shishir Sinha and JN Govil

Book Chapters contributed -

  • Naveen Kumar Navani, Casey Fowler and Yingfu Li (2009) Aptamers for the biosensing of Pathogens. Book Chapter  in Biosensors, Microsystems and the Recognition elements Edited by M. Zourob and APF Turner-Cambridge University, UK.
  • Naveen Kumar Navani, Wendy Mok and Yingfu Li (2009) Aptamer Ligands as sensors for proteins and small molecules. Methods in Biotechnology,”  Humana Press, USA.
  • B. Prakash, N.K. Navani and P.K. Jain (2000) Cytogenetic, blood groups and biochemical polymorphism and molecular genetic characterization of Indian farm animal genetic resources. in “Systems approach to animal farming” eds. R. Nagarcenkar & R.R. Lokeshwar.
  • Naveen Kumar Navani, Pradeep Jain and Rajendra Sahai (2001) DNA technology and its role in biodiversity conservation . in “Current Topics in Environment Biology” Eds. G.Tripathi & G.C. Pandey, pp. 501-514, ABD Publishers(India).
  • Naveen Kumar Navani, Rekha Sharma, Bharani Kumar, S.P.S. Ahlawat and Dinesh Pandey -Exploitation of microbial diversity for bioremediation using genetic tools – book chapter in Biotechnology in Environmental Management - edited by T.K. Ghosh, T. Chakrabarti and G. Tripathi. New Delhi, A.P.H. Pub., 2005, 2 Vols., xxxiv, 715 p

 

Publications
  • Chakarborthy P., Deepankar P., Dash PS., Priya., Srivastva S, Dhayani R., Navani N.K., Sharma D., Sarangi P "Electrostatic Surface Potential of Macrophages Correlates With Their Functional Phenotype" Accepted for publication in Inflammation journal. (Impact factor: 2.9)
  • Bhando, T., Bhattacharyya, T., Gaurav, A., Akhter, J., Saini, M., Gupta, V. K.,Navani N.K... & Biswas, D.Chaudhary R., Pathania R.(2019). Antibacterial properties and in vivo efficacy of a novel nitrofuran, IITR06144, against MDR pathogens. Journal of Antimicrobial Chemotherapy. (Impact factor: 5.2)
  • Dalal, U., Gupta, V. K., Reddy, S. N., & Navani, N. K. (2019). Eradication of Water Borne Pathogens Using Novel Green Nano Ag-Biocomposite of Citrus Limetta Peels. Journal of Environmental Chemical Engineering, 103534. (Impact factor:1.19)
  • T Ghosh, Beniwal, A., Semwal, A., & Navani, N. K. (2019). Mechanistic Insights Into Probiotic Properties of Lactic Acid Bacteria Associated With Ethnic Fermented Dairy Products. Frontiers in Microbiology10, 502. (Impact factor:4.2)
  • Verma, A., Ghosh, T., Bhushan, B., Packirisamy, G., Navani, N. K., Sarangi, P. P., & Ambatipudi, K. (2019). Characterization of difference in structure and function of fresh and mastitic bovine milk fat globules. PloS one, 14(8), e0221830 (Impact Factor: 2.77)
  • T Ghosh, Srivastava, S.K., Gaurav, A., Kumar, A., Kumar, P., Yadav, A.S.,& Navani, N. K. (2019). A combination of linalool, vitamin C, and copper synergistically triggers reactive oxygen species and DNA damage and inhibits Salmonella enteric subsp. enterica serovar Typhi and Vibrio fluvialis. Applied and Environmental Microbiology. 85(4), e02487-18. (Impact factor: 4.0)
  • Kumar, N., Navani, N. K., & Manhas, S. K. (2019). Altering the Schottky Barrier Height and Conductance by Using Metal Nanoparticles in Carbon Nanotubes-Based Devices. IEEE Transactions on Electron Devices66(6), 2789-2794.  (Impact factor: 2.62).
  • R Sharma, P Kumar, V Kaushal, R Das, Naveen K. Navani (2018) A novel protein tyrosine phosphatase like phytase from Lactobacillus fermentum NKN51: Cloning, characterization and application in mineral release for food technology applications. Bioresource Technology 249:1000-1008. (Impact factor: 6.6)
  • SK Srivastava, VR Iyer, T Ghosh, PR Lambadi, R Pathania, Naveen K. Navani (2016) Isolation of a non-genomic origin fluoroquinolones responsive regulatory element using a combinatorial bioengineering approach. Nucleic Acids Research. 44(5):2451-61. (Impact factor: 11.1)
  • S Chamoli, P Kumar, Naveen K. Navani, AK Verma (2016) Secretory expression, characterization and docking study of glucose-tolerant β-glucosidase from B. subtilis. International journal of biological macromolecules. 85: 425-433. (Impact factor: 3.67)
  • P Kumar, P Kumar, S Manhas, Naveen K. Navani (2016) A simple method for detection of anionic detergents in milk using unmodified gold nanoparticles. Sensors and Actuators B: Chemical. 233:157-161. (Impact factor: 6.3)
  • M Kaloti, A Kumar, Naveen K. Navani (2015) Synthesis of glucose-mediated Ag–γ-Fe2O3 multifunctional nano-composites in aqueous medium – a kinetic analysis of their catalytic activity for 4-nitrophenol reduction. Green Chemistry. 17: 4786-99. (Impact factor: 9.12)
  • P Kumar, PR Lambadi, Naveen K. Navani (2015) Non-enzymatic detection of ureausing unmodified gold nanoparticles based aptasensor. Biosensors and Bioelectronics. 72:340-7. (Impact factor:  9.5)
  • M Gupta, S Mathur, TK Sharma, M Rana, A Gairola, Naveen K. Navani, R Pathania. (2015) A study on metabolic prowess of Pseudomonas sp. RPT 52 to degrade imidacloprid, endosulfan and coragen. Journal of Hazard Materials. 301:250-8. (Impact factor: 7.6)
  • Supriya D. Patil, R.Sharma, T. Bhattacharyya, P. Kumar, M. Gupta, Bhupinder S. Chaddha, Naveen K. Navani, R. Pathania (2015). Antibacterial potential of a small peptide from Bacillus sp. RPT-0001 and its capping for green synthesis of silver nanoparticles. Journal of Microbiology. 53(9): 643-652. (Impact factor: 1.92)
  • M Gupta, S Aggarwal, Naveen K. Navani, B Choudhury (2015) Isolation and characterization of a protease-producing novel haloalkaliphilic bacterium Halobiforma sp. strain BNMIITR from Sambhar Lake in Rajasthan, India. Annals of microbiology. 65(2): 677-686. (Impact factor: 1.12)
  • PR Lambadi, TK Sharma, P Kumar, P Vasnani, ST Mouli, N Bisht, R Pathania, Naveen K. Navani (2014) Facile bio-functionalization of silver nanoparticles for enhanced antibacterial properties, endotoxin removal and biofilm control. International Journal of Nano medicine. 10:2155. (Impact factor: 4.30)
  • SK Srivastava, PR Lambadi, T Ghosh, R Pathania, Naveen K. Navani (2014) Genetic regulation of spy gene expression in Escherichia coli in the presence of protein unfolding agent ethanol. Gene 548(1): 142-148. (Impact factor: 2.41)
  • P Devi,     SD Patil, P Jeevandham, , Naveen K Navani., ML Singla (2014) Synthesis, characterization and bactericidal activity of silica/silver core-shell nanoparticles. Journal of material Science: Material Medical. DOI 10.1007/ss10856-014-5265-9. (Impact factor: 2.32)
  • R Sharma, S Arya, SD Patil, A Sharma, PK Jain, Naveen K Navani, R Pathania (2014) Identification of novel regulatory small RNAs in Acinetobacter baumannii. PLoS One 9(4): e93833. (Impact factor: 2.80)
  • IN Ghosh, SD Patil, TK Sharma, SK Srivastava, R Pathania, Naveen K Navani (2013) Synergistic action of cinnamaldehyde with silver nanoparticles against spore-forming bacteria: a case for judicious use of silver nanoparticles for antibacterial applications. International Journal of Nanomedicine. 8: 4721-31. doi: 10.2147/IJN.S49649. Epub 2013 Dec 10. (Impact factor: 4.30).
  • SD Patil, R Sharma, S Srivastava, Naveen K Navani, R Pathania (2013) Down regulation of yidCin Escherichia coli by antisense RNA expression results in sensitization to antibacterial essential oils eugenol and carvacrol. PLoS One 8 (3): e57370. (Impact factor: 2.80)
  • WW Mok, Naveen K. Navani, C Barker, BL Sawchyn, J Gu. R Pathania, RD Zhu, ED Brown, Y Li (2009) Identification of a toxic peptide through bidirectional expression of small RNAs. Chembiochem. 10(2):238-41. (Impact factor: 2.84)
  • Naveen K Navani, WK. Mok, Y Li (2008) Aptamer Ligands as sensors for proteins and small molecules. Methods in Biotechnology. 399-415. Humana Press, USA. A Allali- Hassani, MP Pereira, , ED Brown, Y Li (2007) Isolation of DNA aptamers for CDP-ribitol synthase, and characterization of their inhibitory and structural properties. Chembiochem. 8(17):2052-2057. (Impact factor: 2.84)
  • A Craney, T Hohenauer, Y Xu, Naveen K Navani, Y Li, J Nodwell (2007) A synthetic lux CDABE gene cluster optimized for expression in high-GC bacteria. Nucleic Acids Research. 35(6):e46. (Impact factor: 11.2)

Patents Filed:

  1. Naveen Kumar Navani, Ranjana Pathania, Tarun K Sharma, Aradhana Chopra, Manish Rana. CRN019 Development of an aptamer-gold nanoparticles based rapid and sensitive detection system for Salmonella enteric serovarTyphi. Number 907/DEL/2014.
  1. Ranjana Pathania, Naveen K Navani, Atin Sharma, Rajnikant Sharma, Abin Ghosh. Nucleotide sequences specific for detection of Acinetobacter baumannii. Number 906/DEL/2014.
  1. Naveen Kumar Navani, Ranjana Pathania, Tarun K Sharma, MahakSapraCRN018 A system and method of a colorimetric sensor for ureadetection. Number 900/DEL/2014. Dated 28.03.2014.
  2. Naveen Kumar Navani, PiyushKalra, Paramesh R Lambadi. CRN020 - A nucleotide sequence based colorimetric nanosensor for detection of urea. Number 901 /DEL/2014. dated28.03.2014
  1. Naveen Kumar Navani, Tamoghna Ghosh. Asparaginase and its variants – Number: 201811019299 - May 23,2018.
  1. Naveen Kumar Navani, Shahnawaz Ahmad Baba, Piyush Kumar. Single stranded nucleotide sequence specific for binding to Acinetobacter baumannii and uses thereof – Submitted, being filed byBCIL
  1. Naveen Kumar Navani, AnupamaSemwal and ArunBeniwal. Composition and method for development a probiotics edible film and uses thereof- Submitted, being filed byBCIL

 

 

Honors And Awards
Honors
NATIONAL ACADEMY OF DAIRY SCIENCES
2019
Fellow of National Academy of Dairy Science
Uttarakhand Council for Science and Technology
2010
Young Innovator Award
MemberShips
American Society of Microbiology (ASM)
04 Aug 2020 - Present
Member
ADNAT (Association for promotion of DNA fingerprinting and other DNA technologies)
04 Aug 2020 - Present
Joint Secretary
Students
SuperVisions
Molecular investigations and applications of selected GRAS molecules for antibacterial and anticance
01 Jan 2012 - Present
Other Supervisors: -, Scholar: Tamoghna Ghosh
Development of functional nucleic acid based sensors for detection of biological species
01 Jan 2014 - Present
Other Supervisors: -, Scholar: Shahnawaz A Baba
Development of gluten free probiotics food and methods for food pathogen detection
01 Jan 2015 - Present
Other Supervisors: -, Scholar: Anupama Semwal
Synthesis and multifunctional application of biomolecule mediated A-Fe2O3 nanohybrids
01 Jan 2014 - Present
Other Supervisors: Dr. Anil Kumar, Scholar: Mandeep Kaloti
Nanomaterials based biosensors for the detection of Pathogens and small molecules
01 Jan 2013 - Present
Other Supervisors: Dr. Sanjeev Manhas, Scholar: Pardeep Kumar
Development of recombinant whole cell biosensors
01 Jan 2014 - Present
Other Supervisors: -, Scholar: Rajat Dhyani
Screening and characterization of an extracellular protease from halophilic bacterium
01 Jan 2010 - Present
Other Supervisors: Dr. Bijan Choudhury, Scholar: Meenu Gupta
Molecular and Biochemical studies of probiotic properties of Lactobacillus fermentum NKN51
01 Jan 2010 - Present
Other Supervisors: -, Scholar: Rekha Sharma
Diagnostics platform development using DNA aptamers
01 Jan 2017 - Present
Other Supervisors: -, Scholar: Shubham Jain
Aptamers for adulterant detection and Nano-based strategies for pathogen control
01 Jan 2008 - Present
Other Supervisors: -, Scholar: Lambadi Paramesh Ramulu
Carbon nanotube based devices for sensor applications
01 Jan 2013 - Present
Other Supervisors: Dr. Sanjeev Manhas, Scholar: Narender Kumar
Development of a promoter based bacterial reporter system for a sensing stress response
01 Jan 2007 - Present
Other Supervisors: -, Scholar: Santosh Kumar Srivastava
Generation of DNA aptamers for detection of Escherichia coli and Salmonella enterica
01 Jan 2007 - Present
Other Supervisors: -, Scholar: Tarun Kumar Sharma
Molecular investigations and applications of selected GRAS molecules for antibacterial and anticance
04 Aug 2020 - Present
Other Supervisors: , Scholar: Tamoghna Ghosh
Synthesis and multifunctional application of biomolecule mediated Ag-Fe2O3 nanohybrids
04 Aug 2020 - Present
Other Supervisors: Prof. Anil Kumar, Scholar: Mandeep Kaloti
Molecular and Biochemical studies of probiotic properties of Lactobacillus fermentum NKN51
04 Aug 2020 - Present
Other Supervisors: -, Scholar: Rekha Sharma
Aptamers for adulterant detection and Nano-based strategies for pathogen control
04 Aug 2020 - Present
Other Supervisors: -, Scholar: Lambadi Paramesh Ramulu
Development of a promoter based bacterial reporter system for a sensing stress response
04 Aug 2020 - Present
Other Supervisors: -, Scholar: Santosh Kumar Srivastava
Generation of DNA aptamers for detection of Escherichia coli and Salmonella enterica
04 Aug 2020 - Present
Other Supervisors: -, Scholar: Tarun Kumar Sharma
Screening and characterization of an extracellular protease from halophilic bacterium
04 Aug 2020 - Present
Other Supervisors: Dr. Bijan Choudhury, Scholar: Meenu Gupta
Associate Scholars
Shahnawaz A. Baba
Development of functional nucleic acid based sensors for detection of biological species
Tamoghna Ghosh
Metabolic engineering, combinatorial gene engineering
Shubham Jain
Aptamers
Santosh Kumar Srivastava
Antisense RNA expression in prokaryotes
Ajmal Hussain
Probiotics
Rekha Sharma
Probiotics
Paramesh Lambadi
Aptasensors for small molecules and pathogens
Ankita Bhatt
Whole Cell Biosensor
Mandeep Kaloti
Synthesis of composite magnetic nanomaterials and their biotechnological applications
Rajat Dhyani
Whole Cell Biosensors and Chemical Genetics
Tarun Kumar Sharma
In Vitro Evolution and Aptamer Generation
Pardeep Soni
NanoSensors and Bioremediation
Anupama Semwal
Probiotics and Value addition to Millets
Miscellaneous
Events
AROHP-2019, Antibiotic Resistance- One health propective
01 Jan 2019 - Present
ADNAT
Transcriptional responsive Whole-cell Bacterial Biosensors for applications in Metabolic engineering
01 Jan 2019 - Present
Fermented dairy foods and their health benefits
01 Jan 2018 - Present
Bioengineering Approaches for Selection of Synthetic Functional Nucleic Acids
01 Jan 2018 - Present
Innovative Biotechnological Approaches for Improving Animal Health and Productivity
01 Jan 2018 - Present
DNA finger printing and associated DNA technologies
01 Jan 2018 - Present
Molecular insights in to the Probiotic effects of Lactobacilli for creation of New Generation Dairy
01 Jan 2018 - Present
Administrative Positions
Associate Dean of student Welfare
01 Jan 2014 - 01 Jan 2017
Indian Institute of Technology Roorkee
Warden, Azad Bhawan
01 Jan 2009 - 01 Jan 2013
Indian Institute of Technology Roorkee