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Prince Tiwari
Assistant Professor
prince.tiwari[at]bt.iitr.ac.in
+91-1332-285142
Research Interests

Biosketch
Educational Details
Professional Background

Research
Projects
Publications
Patents
Books
Collaborations

Honours and Awards
Honors
Memberships

Teaching Engagements
Teaching Engagements

Students
Supervisions
Associate Scholars

Miscellaneous
Events
Visits
Administrative Positions
Miscellaneous
Research Interests
Structural basis of muscle regulation, Cryo-electron microscopy (Cryo-EM), TEM, Negative staining, metal shadowing, Protein Biochemistry and structural biology
BioSketch
Educational Details
Indian Institute of Science Education and Research (IISER) Mohali, India, Mohali, Punjab, India
2018
Ph.D., Protein Biochemistry, Biophysics
Devi Ahilya University, Indore
2010
M.Sc., Life Sciences
Professional Background
Assistant Professor
24 Jun 2022 - Present
Department of Biosciences and Bioengineering, Indian Institute of Technology, Roorkee
Post Doctoral Associate
05 Nov 2018 - 20 Jun 2022
University of Massachusetts Medical School, USA
Research
Projects
TOPIC START DATE FIELD DESCRIPTION FINANCIAL OUTLAY FUNDING AGENCY OTHER OFFICERS
Cryo-EM structure of cardiac myosin and its relation to hypertrophic cardiomyopathy (HCM) 17 May 2023 Structural biology PI 20 Lacs IIT Roorkee, India N/A
Cryo-EM structure of the Myosin-MLCK complex to explore the mechanism of myosin activation 05 Jun 2025 Cryo-EM and myosin-MLCK structural and functional exploration PI 46.5 Lacs ANRF, India N/A




Publications
Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting heads motif and super-relaxed state of myosin
2022
David V Rasicci, Prince Tiwari, Skylar ML Bodt, Rohini Desetty,Fredrik R Sadler, Sivaraj Sivaramakrishnan, Roger Craig, Christopher M Yengo | eLife Sciences Publications Ltd
Journal: eLife (Impact Factor 8.14)
Cryo-EM structure of the inhibited (10S) form of myosin II.
2020
Shixin Yang*, Prince Tiwari*, Kyoung Hwan Lee, Osamu Sato, Mitsuo Ikebe, Raúl Padrón and Roger Craig. *Equal contribution | Springer Nature
Journal: Nature (Impact Factor 69.5)
Understanding anomalous mobility of proteins on SDS‐PAGE with special reference to the highly acidic extracellular domains of human E‐ and N‐cadherins
2019
Prince Tiwari, Pallavi Kaila, and Purnananda Guptasarma. | Wiley-VCH
Journal: Electrophoresis (Impact Factor 3.6)
Structural-Mechanical and Biochemical Functions of Classical Cadherins at Cellular Junctions: A Review and Some Hypotheses.
2018
Prince Tiwari, Arpita Mrigwani, Harpreet Kaur, Pallavi Kaila, Rajendra Kumar, Purnananda Guptasarma. | Springer Nature
Journal: Biochemical and Biophysical Roles of Cell Surface Molecules (Impact Factor 3.7)
N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase.
2019
Surabhi Soni, Sneha S. Sathe, Rutuja R. Sheth, Prince Tiwari, Rajesh-Kumar N. Vadgama, Annamma Anil Odaneth, Arvind M. Lali & Sanjeev K. Chandrayan | Springer Nature
Journal: Biotechnology for Biofuels (Impact Factor 7.8)
Multiple thermostable enzyme hydrolases on magnetic nanoparticles: An immobilized enzyme- mediated approach to saccharification through simultaneous xylanase, cellulase and amylolytic glucanotransferase action.
2018
Arpana Kumari, Pallavi Kaila, Prince Tiwari, Vishal Singh, Sunaina Kaul, Nitin Singhal, and Purnananda Guptasarma. | Elsevier
Journal: Int J Biol Macromol (Impact Factor 8.0)
Honors And Awards
Honors
University of Massachusetts Medical School, Worcester, USA
2022
American Heart Association (AHA) postdoctoral fellowship
Yale university, NH, USA
2021
Invited speaker at the 6th Cryo-EM symposium (2021),
BPS-USA
2021
Biophysical Society (BPS) travel grant
Indian Institute of Science Education and Research (IISER) Mohali, India
2018
DBT- India travel grant
Indian Institute of Science Education and Research (IISER) Mohali, India
2017
EMBO- Germany Travel Grant
MemberShips
Biophysical Society (USA)
01 Feb 2018 - Present
Member
American Heart Association (AHA)
01 Mar 2021 - Present
Member
Teaching Engagements
Teaching Engagements
Emerging Technologies ( BT-602 )
Autumn
Biomolecular Spectroscopy ( BTN 706 )
Autumn
Biochemistry and Biophysics ( BE-102 )
Spring
Biomolecular Spectroscopy ( BTN-706 )
Spring