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Kaushik Ghosh
Professor
kaushik.ghosh[at]cy.iitr.ac.in
+91-1332-285547
https://bioinorg7.wixsite.com/kghosh
Research Interests

Biosketch
Educational Details
Professional Background

Research
Projects
Publications
Patents
Books
Collaborations

Honours and Awards
Honors
Memberships

Teaching Engagements
Teaching Engagements

Students
Supervisions
Associate Scholars

Miscellaneous
Events
Visits
Administrative Positions
Miscellaneous
Research Interests
Coordination chemistry, Metal complexes and their interactions with DNA and proteins, Inorganic Biochemistry, Catalysis, Organometallic Chemistry
BioSketch
Educational Details
Indian Institute of Technology Kanpur
1996
M.Sc., Chemistry
Univesity of Kalyani
1993
B.Sc., Chemistry (Honours), Mathematics, Physics
Indian Association for the Cultivation of Science
2001
Ph.D., Chemistry
Professional Background
Post-doctoral Researcher
01 Jan 2001 - 01 Jan 2002
Magnetic Resonance Centre, University of Florence, Italy
Post-doctoral Researcher
01 Jan 2002 - 01 Jan 2005
University of California, Santa Cruz, USA
Assistant Professor
01 Jan 2006 - 01 Jan 2012
Department of Chemistry, Indian Institute of Technology Roorkee, India
Associate Professor
01 Jan 2012 - 01 Jan 2018
IIT Roorkee
Research
Projects
TOPIC START DATE FIELD DESCRIPTION FINANCIAL OUTLAY FUNDING AGENCY OTHER OFFICERS
Studies on Manganese Peptide Interaction 01 Jan 2008 Studies on Manganese Peptide Interaction 17.76 Lakh DST New Delhi
Synthesis and characterization of ruthenium complexes and their DNA binding studies 01 Jan 2008 Synthesis and characterization of ruthenium complexes and their DNA binding studies 14.7 Lakh CSIR




Publications

Publications:

  1. Stabilization of Mn(II) and Mn(III) in mononuclear complexes derived from tridentate ligands with N2O donors: Synthesis, crystal structure, superoxide dismutase activity and DNA interaction studies Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Udai P. Singh, Nidhi Goel, J. Inorg. Biochem. 2010, 104, 9-18.
  2. Role of carboxamido nitrogen in mononuclear manganese complex: Superoxide scavenging activity and nuclease activity Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Inorg. Chem. Commun. 2010, 13, 380-383.
  3. Synthesis and reactivity studies on new copper(II) complexes: DNA binding, generation of phenoxyl radical, SOD and nuclease activity Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Vaibhave Aggarawal, Maria Camilla Baratto, Eur. J. Med. Chem. 2010, 45, 3770-3779.
  4. Oxidative Cyclization of a Phenolic Schiff Base and Synthesis of a Cyclometalated Ruthenium Nitrosyl Complex: Photoinduced NO Release by Visible Light. Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh, Nidhi Goel, Inorg. Chem. 2010, 49, 7235–7237.
  5. Novel Diphenoxo-Bridged Dinuclear Zinc Complexes: Generation of Phenoxyl-Radical Species and Nuclease Activity Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Inorg. Chem. 2010, 49, 7614-16.
  6. Synthesis and characterization of a novel ruthenium nitrosyl complex and studies on photolability of coordinated NO Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Inorg. Chem. Commun. 2011, 14, 146-149.
  1. Synthesis, Structural Characterization and DNA Interaction Studies on a Novel Copper Complex: Nuclease Activity via Self−activation Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Nidhi Goel, Inorg. Chem. Commun. 2011, 14, 489-92.
  2. In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupium Ajanta Chakraborty, Neetu Gupta, Kaushik Ghosh, Partha Roy Toxicology in Vitro, 2010, 24, 1215-1228.
  3. Evaluation of a Schiff base copper complex compound as potent anticancer molecule with multiple targets of action   Ajanta Chakraborty, Pramod Kumar, Kaushik Ghosh, Partha Roy, European Journal of Pharmacology, 2010, 647, 1-12.
  4. Efficient nuclease activity of dinuclear iron(III) complex derived from dinucleating ligand having carboxamido nitrogen donors Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Udai P. Singh, Nidhi Goel Inorg. Chem. Commun. 2012, 20, 167-171.
  5. DNA interaction, superoxide scavenging and cytotoxicity studies on new copper(II) complexes derived from tridentate ligand Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi, Udai P. Singh, Nidhi Goel, Ajanta Chakravorty, Partha Roy, Maria Camilla Baratto  Polyhedron, 2011, 30, 2667-2677.
  6. Photocleavage of Coordinated NO under Visible Light from two Different classes of Organometallic Ruthenium Nitrosyl Complexes: Reversible Binding of Phenolato Function Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh, Nidhi Goel  Organometallics, 2011, 30, 2498-2505.
  7. Synthesis, crystal structure and DNA interaction studies on mononuclear zinc complexes Kaushik Ghosh, Pramod Kumar, Nidhi Tyagi Inorg. Chim. Acta 2011, 375, 77-83.
  8. Self-activated DNA cleavage and NO reactivity studies on mononuclear copper complexes Kaushik Ghosh, Pramod Kumar, Varun Mohan, Udai P. Singh Inorg. Chem. Commun., 2012, 15, 50-56.
  9. Ruthenium(III) Cyclometalates Obtained by Site-Specific Orthometallation and Their Reactivity with Nitric Oxide: Photoinduced Release and Estimation of NO Liberated from the Ruthenium Nitrosyl Complexes Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh Eur. J.  Inorg.  Chem. 2012, 929-938.
  10. Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway Ajanta Chakraborty, Naganjaneyulu Bodipati, Marija Krstic Demonacos, Ramakrishna Peddinti  Kaushik Ghosh  Partha Roy  Molecular and Cellular Endocrinology 2012, 355, 25-40.
  11. Synthesis and structures of mononuclear cobalt complexes derived from tridentate ligands: DNA Binding and Nuclease Activity Studies Kaushik Ghosh, Varun Mohan, Pramod Kumar, Udai P. Singh Polyhedron 2013,  49, 167- 176.
  12. Nuclease Activity via Self-Activation and Anticancer Activity of a Mononuclear Copper(II) Complex: Novel Role of the Tertiary Butyl Group in the Ligand Frame Kaushik Ghosh, Pramod Kumar, Varun Mohan, Udai P. Singh, Sahba Kasiri, and Subhrangsu S. Mandal  Inorg. Chem.201251,3343–3345.
  13. Donation and Scavenging of Nitric Oxide (NO) by Flipping of Denticity of Carboxylate Ligand in Novel Ruthenium Complexes: Photolability of Coordinated NO Kaushik Ghosh, Sushil Kumar, Rajan Kumar. Inorg. Chim. Acta 2013, 405, 24-30. 
  14. Synthesis and characterization of chromium(III) complexes derived from tridentate ligands: Generation of phenoxyl radical and catalytic oxidation of olefins Kaushik Ghosh, Pramod Kumar, Isha Goyal Inorg. Chem. Commun., 2012, 24, 81-86.
  15. Synthesis, characterization and photochemical properties of some ruthenium nitrosyl complexes  A. Kumar, R. Pandey, R. K. Gupta, Kaushik Ghosh, D. S. Pandey Polyhedron2013, 52,  837-843.
  16. Syntheses, structures and properties of ruthenium complexes of tridentate ligands: isolation and characterization of a rare example of ruthenium nitrosyl complex containing {RuNO}5 moiety Kaushik Ghosh, Rajan Kumar, Sushil Kumar Dalton Trans, 2013, 42, 13444-52.
  17. Sensing of Fe(III) ion via turn-on fluorescence by fluorescence probes derived from 1-naphthylamine Kaushik Ghosh, S. Rathi, R.Khuswaha Tetrahedron  Letters, 2013, 54, 6460-63.
  18. Ruthenium(II) complexes derived from the ligands having carboxamide groups: Reactivity and scavenging of nitric oxide (NO) Kaushik Ghosh, S. Kumar, R. Kumar, U. P. Singh  J. Orgmet. Chem., 2014, ASAP article.

  19. Synthesis, structure, redox properties and DNA interaction studies of mononuclear iron(III) complexes with amidate ligand Kaushik Ghosh, Nidhi Tyagi, Pramod Kumar, Udai P. Singh Inorg. Chim. Acta, 2014, ASAP article.

Honors And Awards
Honors
University of Kalyani
1993
Certificate of Merit and Gold Medal , First Class First
DST New Delhi
2007
DST-SERC Fast Track Scheme for Young Scientists
MemberShips
CRSI, INDIA
04 Aug 2020 - Present
Life member
DNA Society of India
04 Aug 2020 - Present
Life member
American Chemical Society
04 Aug 2020 - Present
Member
Teaching Engagements
Teaching Engagements
Chemistry of Main Group and Transition Elements ( CY-512 )
Spring
Advance Inorganic Chemistry - II ( CY-622(I) )
Spring
Advanced Coordination Chemistry ( CY-631 )
Autumn
Basic Inorganic Chemistry ( CY-202M )
Autumn
Chemistry Common Course ( CY101 )
Autumn
Quantum mech and Chemical Bonding ( CY-511 )
Autumn
Chemistry Common Course ( CY-101 )
Spring
Students
SuperVisions
Studies on iron and manganese complexes of polydentate ligands
04 Aug 2020 - Present
Other Supervisors: , Scholar: Nidhi Tyagi
Study on some cancer marker genes and their relation with herbal and synthetic anticancer molecules
04 Aug 2020 - Present
Other Supervisors: Dr. Partha Roy, Scholar: Ajanta Chakravorty
Studies on copper and zinc complexes of polydentate ligands
04 Aug 2020 - Present
Other Supervisors: , Scholar: Pramod Kumar
Studies on ruthenium chemistry
04 Aug 2020 - Present
Other Supervisors: , Scholar: Sushil Kumar
Studies on chemistry of some polydentate ligands and their metal complexes
04 Aug 2020 - Present
Other Supervisors: , Scholar: Varun Mohan
Benzothiazole derivatives for elctro-optical applications
04 Aug 2020 - Present
Other Supervisors: Dr. K. R. Justin Thomas, Scholar: B.M.N.K. Prasad
Some aspects of manganese and iron chemistry with polydentate ligands
04 Aug 2020 - Present
Other Supervisors: , Scholar: Sweety Rathi
Some aspects of chemistry of ruthenium with polydentate ligands
04 Aug 2020 - Present
Other Supervisors: G. Bhattacharjee, Scholar: Rajan Kumar
Studies on some transition metal chelates
04 Aug 2020 - Present
Other Supervisors: , Scholar: Asish K. Dhara
Studies on coordination chemistry of iron and mangananese and their applications
04 Aug 2020 - Present
Other Supervisors: , Scholar: Ovender Singh
organometallic chemistry of Pd and Ru
01 Jan 2013 - Present
Other Supervisors: Kaushik Ghosh, Scholar: Anand Ratan
Associate Scholars
Ashish K. Dhara
Bioinorganic chemistry of copper
Ovender Singh
Coordination chemistry
Anand Ratan
Ruthenium chemistry
Kapil Kumar
Coordination chemistry
Kiran
Coordination Chemistry
Manju Bala
Coordination chemistry
Ankur Maji
Coordination chemistry
Anshu Singh
Coordination chemistry
Sheela Kumari
Coordination chemistry
KDP Lakshmee Kumar
Catalysis
Miscellaneous
Events
Orthometallation and synthesis of ruthenium(III) organometallics: Reactions of nitric oxide
01 Jan 2013 - Present
MTIC XII
04 Aug 2020 - Present
DST
Generation of phenoxyl radical complex: Protease and nuclease activity
01 Jan 2013 - Present
Synthesis of nitrosyl complexes: Controlled delivery of nitric oxide
04 Aug 2020 - Present
Administrative Positions
Member
01 Jan 2006 - 01 Jan 2011
Departmental Research Committee
Faculty Advisor, Table Tennis
01 Jan 2007 - 01 Jan 2008
IIT Roorkee
Member
01 Jan 2011 - Present
Departmental Academic Committee
Exam Coordinator
01 Jan 2009 - Present
Chemistry Department