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Naseem Ahmed
Professor
naseem.ahmed[at]cy.iitr.ac.in
Research Interests

Biosketch
Educational Details
Professional Background

Research
Projects
Publications
Patents
Books
Collaborations

Honours and Awards
Honors
Memberships

Teaching Engagements
Teaching Engagements

Students
Supervisions
Associate Scholars

Miscellaneous
Events
Visits
Administrative Positions
Miscellaneous
Research Interests
Organic synthesis methodology, Medicinal and Radiopharmaceutical probes synthesis
BioSketch
Educational Details
A. M. U. Aligarh, U.P., India
2001
PhD, Chemistry
Professional Background
PostDoctoral fellow
01 Jan 2002 - 01 Jan 2008
University of Sherbrooke, Canada
Research
Projects
TOPIC START DATE FIELD DESCRIPTION FINANCIAL OUTLAY FUNDING AGENCY OTHER OFFICERS
Design, Synthesis and Their Estrogen Receptors Binding Study of Some Novel Flavone, Flavone-Estradio 01 Jan 2012 37 lacs SERB-DST nil
Radiopharmaceutical Chemistry and Molecular Imaging Research 01 Jan 2012 25 lacs BRNS nil
Organic matter transformation, Identification of microbial communities and process kinetics during 01 Jan 2009 30 lacs SERB-DST A. A. Kazmi
Studies of organic pesticides in ground water in Jhasi region 01 Jan 2016 16 lacs UP Govt. nil




Books

Books:

  1. “Synthetic Advances in the Indane Natural Products Scaffolds as Drug Candidates: A Review” Studies in Natural Products Chemistry (Bioactive Natural Products) ELSEVIER SCIENCE PUBLISHERS–AMSTERDAM. 12/2016; 51. DOI:10.1016/B978-0-444-63932-5.00008-5. Pages-383-434.
  2.  Recent advances in molecular scaffolds towards the identification of novel receptors in the treatment of hepatitis diseases, Chapter in Frontiers in Anti-Infective Drug Discovery, ELSEVIER SCIENCE PUBLISHERS–AMSTERDAM. DOI: 10.2174/97816810847941170601 Pages 335-481.
Publications
  1. Mohammed Waheed, Naseem Ahmed and Mohammed Issa Alahmdi, K2S2O8 -Mediated Efficient Oxidative Deoximation of Flavonoid Oximes under Mild Reaction Conditions Chemistry Select, 2019, 4, 7572-7576. 
  2. Danish Khan, Meshari A Alsharif, Naseem Ahmed, SeO2 Mediated Synthesis of Selected Heterocycles by Oxidative C-C Bond Cleavage of Acetophenone Derivatives Chemistry Select, 2019, 4, 7585-7590. 
  3. Mohammed Waheed, Naseem Ahmed and Mohammed Issa Alahmdi, PhI(OAc)2-Mediated One-Pot Synthesis and their Antibacterial Activity of Flavone and Coumarin Based Isoxazoles Under Mild Reaction Condition  Chemistry Select, 2019, 4, 1872-1878.
  4. Meshari A Alsharif, Danish Khan, Naseem Ahmed, Pharmacological activities of novel chromene derivatives as calcium/calmodulin dependent protein kinase IV(CAMKIV) inhibitors, Molecular and Cellular Biochemistry 2019 (Submitted).  
  5. Muzey Bahta, Naseem AhmedA novel 1,​8-​naphthalimide as highly selective naked-​eye and ratiometric fluorescent sensor for detection of Hg2+ ions Journal of Photochemistry and Photobiology, A: Chemistry 2019, 373, 154-161. 
  6. Iram Parveen, Danish Khan and Naseem Ahmed, Regioselective Hydrodehalogenation of Aromatic α- and β-Halo carbonyl Compounds by CuI in Isopropanol European Journal of Organic Chemistry 2019, 759-764. 
  7. Iram Parveen, Naseem Ahmed, Danish Idrees, Parvez Khan, Md. Imtaiyaz Hassan, A Route to Highly Functionalized stereospecific trans-Aminated Aurones from 3-bromoflavones with aniline and N-phenyl urea via a Domino Aza Michael ring opening and cyclization reactions, Synthesis, 2019, 51 (4), 960-970.
  8. Iram Parveen, Naseem Ahmed, Sher Ali, Parvez Khan, Md. Imtaiyaz Hassan, Synthesis, Molecular docking and Inhibition studies of novel 3-N-aryl substituted-2-heteroarylchromones targeting Microtubule Affinity Regulating Kinase 4 Inhibitors,  Eur. J. Med. Chem. 2018, 159, 166-177.
  9. Mohammed Waheed, Mohammed Issa Alahmdi and Naseem Ahmed, One-Pot Synthesis of 1,5-Diketones from 3-acetyl-4-Hydroxycoumarin and Effective Cyclization to Unexpected 3, 4-dihydropyridines, Organic & Biomolecular Chemistry, 2018, 16(18), 3428-3437.
  10. Danish Khan, Mohammed Issa Alahmdi and Naseem Ahmed, KOtBu-Mediated Aza-Michael Addition of Aromatic Amines or N-phenyl urea to 3-nitro-2-phenyl-2H-chromenes and Sequel aerobic dehydrogenation, Eur. J. Org. Chem. 2018, 3454–3463.
  11. Shaily; Kumar, A.; Parveen, I.; Ahmed, N., “Highly selective and sensitive Coumarin-triazole based fluorometric turn-on sensor for detection of Pb2+ ion” Luminescence 2018, 33(4), 713-721.
  12. Muzey Bahta, Naseem Ahmed, Design and synthesis of 1,4-benzothiazine hydrazide as selective and sensitive colorimetric and turn-on fluorometric sensor for Hg2+ detection in aqueous medium, Journal of Photochemistry & Photobiology, A: Chemistry 2018, 357, 41-48.

13. Sumit Kumar, and Naseem Ahmed, "Microwave assisted highly efficient one-pot multi-component synthesis of novel 2-(tetrasubstituted-1H-pyrrol-3-yl)-4H-chroman-4-ones catalyzed by heterogeneous reusable silica gel supported polyphosphoric acid (PPA/SiO2) J. Saudi Chemical Society 2018,  22(2), 136-145.

14.      Shaily, Ajay Kumar and Naseem Ahmed, Coumarin-chalcone hybrid as selective and sensitive colorimetric and turn-on fluorometric sensor for Cd2+ detection, New Journal of Chemistry, 2017, 41(23), 14746-14753.

15.      Mohammed Waheed, Mohammed Issa Alahmdi and Naseem Ahmed, An Efficient Synthesis of 2,​4,​5-​Trisubstituted and 1,​2,​4,​5-​Tetrasubstituted Imidazoles Using Dihydroquinolines as Novel Organocatalyst, Chemistry Select, 2017, 2(26), 7946-7950.

16.      Iram Parveen, Naseem Ahmed, Danish Idrees, Parvez Khan, Md. Imtaiyaz Hassan, Synthesis, estrogen receptor binding affinity and molecular docking of pyrimidine-piperazine-chromene and -quinoline conjugates Bioorganic & Medicinal Chemistry Letters 2017, 27(18), 4493-4499.

17.      Danish Khan, Mohammed Issa Alahmdi and Naseem Ahmed, PhI(OAc)2 mediated an efficient Knoevenagel reaction and their synthetic application for coumarin derivatives, Tetrahedron Letters 2017, 58(32), 3183-3187.

18.       Mohammed Waheed and Naseem Ahmed, Pd/Indanone based ligands: an efficient catalyst system for Ullmann-type, Suzuki-Miyaura, and Mizoroki-Heck cross-coupling reactions with aryl tosylates and aryl halides, Synthesis, 2017, 49, 4372-4382.

19.      Shaily, Ajay Kumar and Naseem Ahmed, An indirect approach for CN- detection: Development of "Naked-Eye" Hg2+ induced turn-off fluorescence and turn-on cyanide sensing via Hg2+ displacement approach. Industrial & Engineering Chemistry Research 2017, 56 (22), 6358-6368.

20.      Iram Parveen, Naseem Ahmed, CuI mediated synthesis of heterocyclic flavone-benzofuran fused derivatives Tetrahedron Letters 2017, 58(23), 2302-2305.

21.      Nishant Verma, Sumit Kumar, Naseem Ahmed, LiBr/β-CD/IBX/ H2O-DMSO: A new approach for one pot biomimetic regioselective ring opening of chalcone epoxides to bromohydrins and conversion to 1,2,3-triketones Synth. Comm. 2017, 47(11), 1110-1120.

22.      Kumar, Sumit; Verma, Nishant; Zubair, Swaleha; Faisal, Syed Mohd.; Kazmi, Shadab; Chakraborty, Sudipta; Owais, M.; Naseem Ahmed Design and Synthesis of Novel Nonsteroidal Phytoestrogen-based Probes as Potential Biomarker: Evaluation of Anticancer Activity and Docking Studies J. Heterocyclic Chemistry 2017, 54(4), 2242-2257.

23.  Shaily, Ajay Kumar and Naseem Ahmed, Imidazo[1,2-a]pyridine substituted coumarin as a selective ratiometric sensor for Cu2+ ion, Supramolecular Chemistry, 2017, 29(2), 146-152.

24.  Shaily; Kumar, Ajay; Kumar, Sumit; Ahmed, Naseem 'Naked-eye' colorimetric/fluorimetric detection of F- ions by biologically active 3-((1H-indol-3-yl)methyl)-4-hydroxy-2H-chromen-2-one derivatives RSC Advances 2016, 6 (109), 108105-108112.

25.  Naseem Ahmed, Chapter: Synthetic Advances in the Indane Natural Product Scaffolds as Drug Candidates Studies in Natural Products Chemistry 12/2016; 51. DOI:10.1016/B978-0-444-63932-5.00008-5. 383-434.

26.  Sumit Kumar, Nishant Verma, Iram Parveen and Naseem Ahmed, A green, solvent-free, microwave assisted, high yielding YbCl3catalysed deprotection of THP/MOM/Ac/Ts ethers of chalcone epoxide and 2’-aminochalcone and their sequel cyclization J. Heterocyclic Chemistry, 2016, 53(6), 2111-2122.

27.  Mohammed Waheed and Naseem Ahmed, Coumarin Based Novel Ligands in the Suzuki-Miyaura and Mizoroki-Heck Cross-Couplings under Aqueous Medium Tetrahedron Letters 2016, 57(33), 3785-3789.

15.  Nishant Verma, Sumit Kumar, Naseem Ahmed, Asymmetric Organocatalytic Synthesis of 3-Benzofuranones through 5-Exo-trig cyclization of 4-Nitroaryl olefins, Tetrahedron Letters 2016, 57(31), 3547-3550.

28.  Sumit Kumar and Naseem Ahmed, β-Cyclodextrin/IBX in water: Highly facile biomimetic one pot deprotection of THP/MOM/Ac/Ts ethers and concomitant oxidative cleavage of chalcone epoxides and oxidative dehydrogenation of alcohols, Green Chemistry, 2016, 18(3), 648-656.

29.  Ali, Muntjeer; Gani, Khalid M.; Kazmi, Absar A.; Naseem Ahmed, Degradation of aldrin and endosulfan in rotary drum and windrow composting, Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes 2016, 51(5), 278-286.

30.   Nishant Verma, Sumit Kumar, and Naseem Ahmed, A facile access to novel heterocyclic analogues of chalcone from newly synthesized ketone containing isoxazole and benzoxazinone ring, RSC Advances, 2016, 6(56), 51183-51191.

31.  Sumit Kumar, and Naseem Ahmed, "Microwave assisted highly efficient one-pot multi-component synthesis of novel 2-(tetrasubstituted-1H-pyrrol-3-yl)-4H-chroman-4-ones catalyzed by heterogeneous reusable silica gel supported polyphosphoric acid (PPA/SiO2) J. Saudi Chemical Society 2016,  accepted.

32.  Sumit Kumar, Nishant Verma, Nikhil Kumar, Alok Patel, Partha Roy, Vikas Pruthi, Naseem Ahmed Design, Synthesis, Molecular docking and Biological studies of Novel Phytoestrogen-Tanaproget hybrids, Synthetic Communication 2016, 46(5), 460-474.

 

Honors And Awards
MemberShips
Indian Chemical Society
07 Jul 2020 - Present
Fellow
The Indian Science Congress Association
07 Jul 2020 - Present
Fellow
Teaching Engagements
Teaching Engagements
Drug design and action ( CYN-762 )
Spring
Organic and Inorganic chemistry ( CYH-002 )
Spring
Organic structure determination ( CYN-621 )
Spring
Inorganic chemistry ( CY-101 )
Spring
Pharmaceutical chemistry ( CYN-722 )
Spring
Structure and reactivity of Organic molecules ( CYN-507 )
Autumn
Characterization techniques ( CY-731 )
Spring
Adv. organic chemistry II ( CY-645 )
Autumn
Adv. organic chemistry I ( CY-635 )
Autumn
organic chemistry ( CY-101 )
Spring
Green Chemistry ( CY-212 )
Spring
Students
SuperVisions
Organic matter transformation including trace organics during rotary drum composting
01 Jan 2008 - Present
Other Supervisors: A. A. Kazmi, Scholar: Mr. Muntajeer Ali
Design, synthesis and characterization of chalcone based derivatives
01 Jan 2009 - Present
Other Supervisors: -, Scholar: Mr. B. V. Babu
Synthesis of benzoxazine derivatives using 2-amminophenol precursors
01 Jan 2009 - Present
Other Supervisors: R. K. Peddinti , Scholar: Mr. Ram Tilak Naganaboina
Design, synthesis and biological evaluation of functionalized flavonoids derivatives
01 Jan 2009 - Present
Other Supervisors: -, Scholar: Mr. Naveen Kumar K
Design, Synthesis and Estrogen Receptor Binding Study of Flavone and Indanone Based Ligands
01 Jan 2012 - Present
Other Supervisors: -, Scholar: Mr. Gulabrao Pathe
Design, synthesis and biological evaluation of novel flavonoid derivatives
01 Jan 2012 - Present
Other Supervisors: -, Scholar: Mr. Sumit Kumar
Design and synthesis of flavonoids derivatives, their biological and in-silico studies
01 Jan 2012 - Present
Other Supervisors: -, Scholar: Mr. Nishant Verma
Synthesis and Biological Applications of Flavonoid Based Natural Products
01 Jan 2013 - Present
Other Supervisors: -, Scholar: Ms. Iram Praveen
Synthesis and Characterization of Flavone, Coumarin, Imidazole and Isoxazole Derivatives Using Novel
01 Jan 2014 - Present
Other Supervisors: -, Scholar: Mohd. Waheed
Design, synthesis and evaluation of some novel fluorescent chemosensers for Mercury (II) ion detect
01 Jan 2015 - Present
Other Supervisors: -, Scholar: Ms. Muzey Behata
Synthesis and Applications of Novel Ligands in Coupling reactions
01 Jan 2016 - Present
Other Supervisors: -, Scholar: Danish Khan
Design, Synthesis and characterization of coumarin derivatives as chemosensors
01 Jan 2012 - Present
Other Supervisors: Anuj Sharma, Scholar: Ms. Shaily
Miscellaneous
Events
Synthesis of Radiopharmaceuticals in Imaging
01 Jan 2007 - Present
Faculty position
01 Jan 2018 - Present
Administrative Positions
Dy Chairman, Community Dairy
01 Jan 2012 - 01 Jan 2015
Indian Institute of Technology Roorkee