Research Interests
Organic synthesis methodology, Medicinal and Radiopharmaceutical probes synthesis
BioSketch
Research
Direct one-pot synthesis of tetrazole derivatives from aldehydes under metal-free conditions
2025
Rajeev Singh, Naseem Ahmed | Thieme
Journal: Synlett Pages: 1003-1008 , Volumes: 36 ,
A Facile Route Through Iodine-Mediated Synthesis of Isoxazole Derivatives from Chalcone Epoxide
2025
Avijit Bhakta, Naseem Ahmed | Wiley
Journal: ChemistrySelect Pages: e202405034 , Volumes: 10 ,
Solvent-assisted efficient syntheses of 1,3,5-triaryl-1H-pyrazoles via ring opening and cyclization in chalcone epoxides
2025
Avijit Bhakta, Naseem Ahmed | Wiley
Journal: ChemistrySelect Pages: e05920 , Volumes: 10 ,
Nickel(II)-hydrazineylpyridine catalyzed regioselective synthesis of ?-benzyl substituted ?-hydroxy ketones via a Fenton free radical reaction
2025
Apurva Singh, Naseem Ahmed | RSC
Journal: Org. Biomol. Chem. Pages: 1689 , Volumes: 23 ,
Design and Synthesis of novel Coumarin - Isoxazole conjugates as Chemosensers: a highly Selective and Instantaneous Detection of Mn2+ and Cu2+ Ions
2025
Sonam, Avijit Bhakta, Naseem Ahmed | Wiley
Journal: Luminescence Pages: e70293 , Volumes: 40 ,
Design and Synthesis of Novel 4-Hydroxycoumarin-Isoxazole Adducts for Combating Bacterial Infections
2025
Avijit Bhakta, Naseem Ahmed et. al | Elsevier
Journal: Journal of Molecular Structure Pages: 142668 , Volumes: 1328 ,
Nickel Chloride Hexahydrate-Catalyzed Regioselective Synthesis of Quinolines and Bis-Quinolines Under Aerial Oxidation
2025
Apurva Singh, Naseem Ahmed | Wiley
Journal: Eur. J. Org. Chem. Pages: e202500274 , Volumes: 28 ,
Dehydrogenation of Primary Alcohols via Radical Pathway by NNO Pincer-Derived Manganese Complexes
2026
Apurva Singh, Naseem Ahmed | Wiley
Journal: Applied Organometallic Chemistry Pages: e70575 , Volumes: 40 ,
Oxidative cyclization reactions catalyzed by designed transition metal complexes: A new strategy for the synthesis of flavone, quinolones and benzofuran derivatives
2023
A. Singh, S. Singh, K. Ghosh and Naseem Ahmed | Thieme
Journal: Synthesis Pages: 4191-4203 , Volumes: 55 (24) ,
Recent advances and emerging opportunities in mechanism and applications of earth abundant manganese-catalysts for sustainable organic transformations
2024
Naseem Ahmed | Elsevier
Journal: J. Organomet. Chem. Pages: 123071 , Volumes: 1009 ,
Divergent Synthesis of Fused Benzo-xanthene and Oxazine derivatives via Cu-catalyst
2022
Meshari A Alsharif, Naseem Ahmed, Mohammed Issa Alahmdi, Sayeed Mukhtar, Humaira Parveen, Rami J. Obaid and Abdulraheem SA Almalki | Springer
Journal: J. Saudi Chem. Pages: 101568 , Volumes: 26 ,
Design, synthesis, molecular docking and anti-proliferative activity of novel phenothiazine containing imidazo[1,2-a]pyridine derivatives against MARK4 protein
2024
Avijit Bhakta, Naseem Ahmed et. al | RSC
Journal: RSC Med. Chem. Pages: 1942-1958 , Volumes: 15 ,
Advances and emerging trends in mechanistic insights of Sonogashira-type coupling reactions towards Green Protocols for sustainable organic transformations
2024
Naseem Ahmed | Elsevier
Journal: J. Organomet. Chem. Pages: 123243 , Volumes: 1016 ,
Organocatalytic synthesis of novel pyrazoline and pyrimidine derivatives as potent thymidine kinase inhibitors targeting Staphylococcus aureus
2025
Mohammed Issa Alahmdia, Avijit Bhakta, Meshari A. Alsharif, Sayeed Mukhtara, Humaira Parveena, Apurva Singh, Nader E. Abo-Dyad, Yahya Hamed Yahya Almalkya, Mohmmad Younus Wanie, Naseem Ahmed | Elsevier
Journal: Journal of Molecular Structure Pages: 141427 , Volumes: 1328 ,
Enhancing the potential of Michael addition reaction using Betti base-Thiourea-driven organocatalysis for one-pot synthesis of 2,4-disubstituted pyrroles
2025
Rajeev Singh and Naseem Ahmed | RSC
Journal: Catalysis Science & Tech. Pages: 6027–6034 , Volumes: 15 ,
Integrated Computational and Experimental Examination of Schiff base (E)-2-methoxy-6-((2-phenyl-2-(pyridin-2-yl)hydrazono) methyl)phenol
2026
Apurva Singh, Sultan, Mohammad Jane Alam, Naseem Ahmed, S. M. Afzal, Shabbir Ahmad | Elsevier
Journal: Journal of Photochemistry & Photobiology, A: Chemistry Pages: 116662 , Volumes: 470 ,
Phenyl-Driven structural engineering of Pyridyl-Based Schiff bases for enhanced Photophysical and Third-Order non-linear Optical Responses: An Experimental and DFT Study
2026
Sultan, Apurva Singh, Mohammad Jane Alam, M.A.N. Razvi, S.M. Afza, Naseem Ahmed, Shabbir Ahmad | Elsevier
Journal: Journal of Molecular Structure Pages: 146007 , Volumes: 1365 ,
Recent developments in manganese complexes for hydrogenation and dehydrogenation reactions: A comparative overview with iron and nickel catalysts
2026
Apurva Singh, Naseem Ahmed | Elsevier
Journal: Journal of Organometallic Chemistry Pages: 124137 , Volumes: 1053 ,
A Sustainable Approach to Synthesise Tetra- and Penta-Substituted Pyrroles Under Three-Component One-Pot Synthesis Using Novel Thiourea-Derived Organocatalysts
2026
Rajeev Singh, Naseem Ahmed | Wiley
Journal: Asian Journal of Organic Chemistry Pages: e70414 , Volumes: 15 ,
Exploring the bifunctional nature of L-proline for the organocatalytic synthesis of 2-amino 1,3,4-thiadiazoles and 2-amino-1,3,4-oxadiazoles under mild reaction conditions
2026
Rajeev Singh, Naseem Ahmed | Wiley
Journal: Asian Journal of Organic Chemistry Pages: e70340 , Volumes: 15 ,
Solvent-assisted one-pot green and diastereoselective synthesis of 1,4-oxazines and 1,4-thioxazines under metal-free conditions
2026
Farukh Ahmad, Rajeev Singh, Naseem Ahmed | RSC
Journal: Org. Biomol. Chem Pages: 157-162 , Volumes: 24 ,
New N-(Acyloxy) and N-(Benzyloxy)amide Derivatives: Synthesis, Anti-bacterial Activity and Molecular Docking Studies
2026
Ashutosh Dixit, Avijit Bhakta, Nitin, Farhana Naaz, Asghar Ali, Sobia Khan, Tanvi Sharma, Mohan Kamthan, Mohammad Abid, and Naseem Ahmed | Wiley
Journal: Chemistry Select
Honors And Awards
Teaching Engagements
Students
Miscellaneous
- Mohammed Waheed, Naseem Ahmed and Mohammed Issa Alahmdi, K2S2O8 -Mediated Efficient Oxidative Deoximation of Flavonoid Oximes under Mild Reaction Conditions Chemistry Select, 2019, 4, 7572-7576.
- Danish Khan, Meshari A Alsharif, Naseem Ahmed, SeO2 Mediated Synthesis of Selected Heterocycles by Oxidative C-C Bond Cleavage of Acetophenone Derivatives Chemistry Select, 2019, 4, 7585-7590.
- Mohammed Waheed, Naseem Ahmed and Mohammed Issa Alahmdi, PhI(OAc)2-Mediated One-Pot Synthesis and their Antibacterial Activity of Flavone and Coumarin Based Isoxazoles Under Mild Reaction Condition Chemistry Select, 2019, 4, 1872-1878.
- Meshari A Alsharif, Danish Khan, Naseem Ahmed, Pharmacological activities of novel chromene derivatives as calcium/calmodulin dependent protein kinase IV(CAMKIV) inhibitors, Molecular and Cellular Biochemistry 2019 (Submitted).
- Muzey Bahta, Naseem Ahmed, A novel 1,8-naphthalimide as highly selective naked-eye and ratiometric fluorescent sensor for detection of Hg2+ ions Journal of Photochemistry and Photobiology, A: Chemistry 2019, 373, 154-161.
- Iram Parveen, Danish Khan and Naseem Ahmed, Regioselective Hydrodehalogenation of Aromatic α- and β-Halo carbonyl Compounds by CuI in Isopropanol European Journal of Organic Chemistry 2019, 759-764.
- Iram Parveen, Naseem Ahmed, Danish Idrees, Parvez Khan, Md. Imtaiyaz Hassan, A Route to Highly Functionalized stereospecific trans-Aminated Aurones from 3-bromoflavones with aniline and N-phenyl urea via a Domino Aza Michael ring opening and cyclization reactions, Synthesis, 2019, 51 (4), 960-970.
- Iram Parveen, Naseem Ahmed, Sher Ali, Parvez Khan, Md. Imtaiyaz Hassan, Synthesis, Molecular docking and Inhibition studies of novel 3-N-aryl substituted-2-heteroarylchromones targeting Microtubule Affinity Regulating Kinase 4 Inhibitors, Eur. J. Med. Chem. 2018, 159, 166-177.
- Mohammed Waheed, Mohammed Issa Alahmdi and Naseem Ahmed, One-Pot Synthesis of 1,5-Diketones from 3-acetyl-4-Hydroxycoumarin and Effective Cyclization to Unexpected 3, 4-dihydropyridines, Organic & Biomolecular Chemistry, 2018, 16(18), 3428-3437.
- Danish Khan, Mohammed Issa Alahmdi and Naseem Ahmed, KOtBu-Mediated Aza-Michael Addition of Aromatic Amines or N-phenyl urea to 3-nitro-2-phenyl-2H-chromenes and Sequel aerobic dehydrogenation, Eur. J. Org. Chem. 2018, 3454–3463.
- Shaily; Kumar, A.; Parveen, I.; Ahmed, N., “Highly selective and sensitive Coumarin-triazole based fluorometric turn-on sensor for detection of Pb2+ ion” Luminescence 2018, 33(4), 713-721.
- Muzey Bahta, Naseem Ahmed, Design and synthesis of 1,4-benzothiazine hydrazide as selective and sensitive colorimetric and turn-on fluorometric sensor for Hg2+ detection in aqueous medium, Journal of Photochemistry & Photobiology, A: Chemistry 2018, 357, 41-48.
13. Sumit Kumar, and Naseem Ahmed, "Microwave assisted highly efficient one-pot multi-component synthesis of novel 2-(tetrasubstituted-1H-pyrrol-3-yl)-4H-chroman-4-ones catalyzed by heterogeneous reusable silica gel supported polyphosphoric acid (PPA/SiO2) J. Saudi Chemical Society 2018, 22(2), 136-145.
14. Shaily, Ajay Kumar and Naseem Ahmed, Coumarin-chalcone hybrid as selective and sensitive colorimetric and turn-on fluorometric sensor for Cd2+ detection, New Journal of Chemistry, 2017, 41(23), 14746-14753.
15. Mohammed Waheed, Mohammed Issa Alahmdi and Naseem Ahmed, An Efficient Synthesis of 2,4,5-Trisubstituted and 1,2,4,5-Tetrasubstituted Imidazoles Using Dihydroquinolines as Novel Organocatalyst, Chemistry Select, 2017, 2(26), 7946-7950.
16. Iram Parveen, Naseem Ahmed, Danish Idrees, Parvez Khan, Md. Imtaiyaz Hassan, Synthesis, estrogen receptor binding affinity and molecular docking of pyrimidine-piperazine-chromene and -quinoline conjugates Bioorganic & Medicinal Chemistry Letters 2017, 27(18), 4493-4499.
17. Danish Khan, Mohammed Issa Alahmdi and Naseem Ahmed, PhI(OAc)2 mediated an efficient Knoevenagel reaction and their synthetic application for coumarin derivatives, Tetrahedron Letters 2017, 58(32), 3183-3187.
18. Mohammed Waheed and Naseem Ahmed, Pd/Indanone based ligands: an efficient catalyst system for Ullmann-type, Suzuki-Miyaura, and Mizoroki-Heck cross-coupling reactions with aryl tosylates and aryl halides, Synthesis, 2017, 49, 4372-4382.
19. Shaily, Ajay Kumar and Naseem Ahmed, An indirect approach for CN- detection: Development of "Naked-Eye" Hg2+ induced turn-off fluorescence and turn-on cyanide sensing via Hg2+ displacement approach. Industrial & Engineering Chemistry Research 2017, 56 (22), 6358-6368.
20. Iram Parveen, Naseem Ahmed, CuI mediated synthesis of heterocyclic flavone-benzofuran fused derivatives Tetrahedron Letters 2017, 58(23), 2302-2305.
21. Nishant Verma, Sumit Kumar, Naseem Ahmed, LiBr/β-CD/IBX/ H2O-DMSO: A new approach for one pot biomimetic regioselective ring opening of chalcone epoxides to bromohydrins and conversion to 1,2,3-triketones Synth. Comm. 2017, 47(11), 1110-1120.
22. Kumar, Sumit; Verma, Nishant; Zubair, Swaleha; Faisal, Syed Mohd.; Kazmi, Shadab; Chakraborty, Sudipta; Owais, M.; Naseem Ahmed Design and Synthesis of Novel Nonsteroidal Phytoestrogen-based Probes as Potential Biomarker: Evaluation of Anticancer Activity and Docking Studies J. Heterocyclic Chemistry 2017, 54(4), 2242-2257.
23. Shaily, Ajay Kumar and Naseem Ahmed, Imidazo[1,2-a]pyridine substituted coumarin as a selective ratiometric sensor for Cu2+ ion, Supramolecular Chemistry, 2017, 29(2), 146-152.
24. Shaily; Kumar, Ajay; Kumar, Sumit; Ahmed, Naseem 'Naked-eye' colorimetric/fluorimetric detection of F- ions by biologically active 3-((1H-indol-3-yl)methyl)-4-hydroxy-2H-chromen-2-one derivatives RSC Advances 2016, 6 (109), 108105-108112.
25. Naseem Ahmed, Chapter: Synthetic Advances in the Indane Natural Product Scaffolds as Drug Candidates Studies in Natural Products Chemistry 12/2016; 51. DOI:10.1016/B978-0-444-63932-5.00008-5. 383-434.
26. Sumit Kumar, Nishant Verma, Iram Parveen and Naseem Ahmed, A green, solvent-free, microwave assisted, high yielding YbCl3catalysed deprotection of THP/MOM/Ac/Ts ethers of chalcone epoxide and 2’-aminochalcone and their sequel cyclization J. Heterocyclic Chemistry, 2016, 53(6), 2111-2122.
27. Mohammed Waheed and Naseem Ahmed, Coumarin Based Novel Ligands in the Suzuki-Miyaura and Mizoroki-Heck Cross-Couplings under Aqueous Medium Tetrahedron Letters 2016, 57(33), 3785-3789.
15. Nishant Verma, Sumit Kumar, Naseem Ahmed, Asymmetric Organocatalytic Synthesis of 3-Benzofuranones through 5-Exo-trig cyclization of 4-Nitroaryl olefins, Tetrahedron Letters 2016, 57(31), 3547-3550.
28. Sumit Kumar and Naseem Ahmed, β-Cyclodextrin/IBX in water: Highly facile biomimetic one pot deprotection of THP/MOM/Ac/Ts ethers and concomitant oxidative cleavage of chalcone epoxides and oxidative dehydrogenation of alcohols, Green Chemistry, 2016, 18(3), 648-656.
29. Ali, Muntjeer; Gani, Khalid M.; Kazmi, Absar A.; Naseem Ahmed, Degradation of aldrin and endosulfan in rotary drum and windrow composting, Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes 2016, 51(5), 278-286.
30. Nishant Verma, Sumit Kumar, and Naseem Ahmed, A facile access to novel heterocyclic analogues of chalcone from newly synthesized ketone containing isoxazole and benzoxazinone ring, RSC Advances, 2016, 6(56), 51183-51191.
31. Sumit Kumar, and Naseem Ahmed, "Microwave assisted highly efficient one-pot multi-component synthesis of novel 2-(tetrasubstituted-1H-pyrrol-3-yl)-4H-chroman-4-ones catalyzed by heterogeneous reusable silica gel supported polyphosphoric acid (PPA/SiO2) J. Saudi Chemical Society 2016, accepted.
32. Sumit Kumar, Nishant Verma, Nikhil Kumar, Alok Patel, Partha Roy, Vikas Pruthi, Naseem Ahmed Design, Synthesis, Molecular docking and Biological studies of Novel Phytoestrogen-Tanaproget hybrids, Synthetic Communication 2016, 46(5), 460-474.